Receptor-Free Signaling at Curved Cellular Membranes.

Autor: Ebrahimkutty MP; DFG Cluster of Excellence 'Cells in Motion', University of Muenster, Muenster, 48149, Germany.; Institute of Medical Physics and Biophysics, University of Muenster, Muenster, 48149, Germany.; CIM-IMRPS Graduate School, Muenster, 48149, Germany., Galic M; DFG Cluster of Excellence 'Cells in Motion', University of Muenster, Muenster, 48149, Germany.; Institute of Medical Physics and Biophysics, University of Muenster, Muenster, 48149, Germany.
Jazyk: angličtina
Zdroj: BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2019 Oct; Vol. 41 (10), pp. e1900068. Date of Electronic Publication: 2019 Sep 04.
DOI: 10.1002/bies.201900068
Abstrakt: Plasma membranes are subject to continuous deformations. Strikingly, some of these transient membrane undulations yield membrane-associated signaling hubs that differ in composition and function, depending on membrane geometry and the availability of co-factors. Here, recent advancements on this ubiquitous type of receptor-independent signaling are reviewed, with a special focus on emerging concepts and technical challenges associated with studying these elusive signaling sites.
(© 2019 The Authors. BioEssays Published by Wiley Periodicals, Inc.)
Databáze: MEDLINE
Externí odkaz: