The Pitfall of Utilizing a Commercial Biochemical Yeast Identification Kit to Detect Candida auris .

Autor:	Ding CH; Department of Medical Microbiology & Immunology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur dingch@ppukm.ukm.edu.my., Situ SF; Microbiology Unit, Department of Pathology, Hospital Umum Sarawak, Ministry of Health of Malaysia, Kuching, Sarawak., Steven A; Infectious Diseases Unit, Department of Medicine, Hospital Umum Sarawak, Ministry of Health of Malaysia, Kuching, Sarawak., Razak MFA; Infectious Diseases Research Centre, Institute for Medical Research, Ministry of Health of Malaysia, Kuala Lumpur, Malaysia.
Jazyk:	angličtina
Zdroj:	Annals of clinical and laboratory science [Ann Clin Lab Sci] 2019 Sep; Vol. 49 (4), pp. 546-549.
Abstrakt:	Candida auris is an emerging pathogenic yeast responsible for nosocomial infections with high mortality, on a global scale. A 65-year-old woman with hypovolemic shock and severe metabolic acidosis was intubated and admitted to the intensive care unit (ICU). Shortly after admission, she developed ventilator-associated pneumonia caused by multidrug-resistant Acinetobacter baumannii , which necessitated treatment with high-dose ampicillin-sulbactam. Two weeks later, a yeast was cultured from her blood. It formed pale pink colonies on CHROMagar Candida medium and produced predominantly oval budding yeast cells with the occasional rudimentary pseudohyphae on cornmeal agar. ID 32 C identified the yeast as Candida sake However, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and sequencing of the D1/D2 region of the 28S rRNA gene identified the yeast as C. auris . (© 2019 by the Association of Clinical Scientists, Inc.)
Databáze:	MEDLINE
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