Anti-inflammatory secondary metabolites from the stems of Millettia dielsiana Harms ex Diels.

Autor: Dat LD; Division of Computational Physics, Institute for Computational Science, Ton Duc Thang University, Ho Chi Minh City, Viet Nam; Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Viet Nam. Electronic address: leducdat@tdtu.edu.vn., Tu NTM; School of Biotechnology and Food Technology, Hanoi University of Science and Technology, Hanoi, Viet Nam. Electronic address: tu.nguyenthiminh@hust.edu.vn., Duc NV; Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Viet Nam. Electronic address: ngovietduc@tdtu.edu.vn., Luyen BTT; Hanoi Univerisity of Pharmacy, 13-15, Le Thanh Tong, Hanoi, Viet Nam. Electronic address: luyenbthoaduoc@gmail.com., Huyen CTT; Hanoi Univerisity of Pharmacy, 13-15, Le Thanh Tong, Hanoi, Viet Nam. Electronic address: chuthanhhuyen@qq.com., Jang HJ; Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeonbuk, 56212, Republic of Korea. Electronic address: water815@kribb.re.kr., Thu DT; School of Biotechnology and Food Technology, Hanoi University of Science and Technology, Hanoi, Viet Nam. Electronic address: dangthudhbk@yahoo.com., Huong TT; School of Chemical Engineering, Hanoi University of Science and Technology, Hanoi, Viet Nam. Electronic address: huong.tranthu@hust.edu.vn., Tram LH; School of Chemical Engineering, Hanoi University of Science and Technology, Hanoi, Viet Nam. Electronic address: huyentramle@gmail.com., Thong NV; School of Chemical Engineering, Hanoi University of Science and Technology, Hanoi, Viet Nam. Electronic address: nguyenvanthong227@yahoo.com., Hung ND; Centre for Drug Research and Technology Transfer, Phutho College of Medicine and Pharmacy, Viettri City, Phutho Province, Viet Nam., Kim YH; College of Pharmacy, Chungnam National University, Daejeon, 34134, Republic of Korea. Electronic address: yhk@cnu.ac.kr., Thao NP; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam. Electronic address: thaonp@imbc.vast.vn.
Jazyk: angličtina
Zdroj: Carbohydrate research [Carbohydr Res] 2019 Oct 01; Vol. 484, pp. 107778. Date of Electronic Publication: 2019 Aug 14.
DOI: 10.1016/j.carres.2019.107778
Abstrakt: A phytochemical investigation for the constituents of the stems of Millettia dielsiana Harms ex Diels resulted in the isolation of a new isoflavone glycoside, mildiside A (1), and 14 known compounds (2-15). Their chemical structures were determined using a combination of IR, NMR, MS, and optical rotation analysis, as well as comparison with the literature data. The ethanolic (EtOH) extract and several isolated compounds exert the inflammatory effect of nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated murine RAW264.7 macrophage cells.
(Copyright © 2019 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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