| Autor: |
Otu AA; Senior Lecturer/Consultant Physician, Department of Internal Medicine, University of Calabar, Calabar, Cross River State, Nigeria., Udoh UA; Lecturer/Consultant Medical Microbiologist, Department of Medical Microbiology and Parasitology, University of Calabar, Calabar, Cross River State, Nigeria., Ita OI; Lecturer/Consultant Medical Microbiologist, Department of Medical Microbiology and Parasitology, University of Calabar, Calabar, Cross River State, Nigeria., Hicks JP; Lecturer in Medical Statistics, Nuffield Centre for International Health, Leeds Institute of Health Sciences, University of Leeds, Leeds, UK., Ukpeh I; Senior Registrar in Internal Medicine, Department of Internal Medicine, University of Calabar, Calabar, Cross River State, Nigeria., Walley J; Clinical Professor of International Public Health, Nuffield Centre of International Health & Development, LIHS, University of Leeds, Leeds, UK. |
| Abstrakt: |
We describe the frequency of Zika and malaria among patients presenting with fever to secondary health facilities in Cross River State, Nigeria. Using a cross-sectional, stratified survey design, we randomly selected nine facilities and consecutively recruited 100 participants (aged ≥ 1 year) who presented with fever. On testing blood samples using Biocan qualitative lateral flow immuno-chromatographic cassettes for Zika IgG and IgM, 10% were seropositive for Zika virus (ZIKV) IgM, 12% for ZIKV IgG and 20% for ZIKV IgM, IgG or both. Following microscopy of thick films stained with Giemsa for malaria parasites, 55% were positive for malaria and 15% were positive for both malaria and ZIKV IgM, IgG or both. A moderately negative association between urban and rural household location and seropositivity for ZIKV IgM or IgG was found on logistic regression. Our results clearly indicate a high rate of probable ZIKV and malaria co-incidence in Cross River State. Given the high risk of serious fetal outcomes following ZIKV infection, further epidemiological research and surveillance systems for ZIKV are clearly required. |
