Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping.

Autor: Mahon BZ; Department of Neurosurgery, University of Rochester Medical Center; Department of Psychology, Carnegie Mellon University; bmahon@andrew.cmu.edu., Mead JA; Public Relations and Communications, University of Rochester Medical Center., Chernoff BL; Department of Psychology, Carnegie Mellon University., Sims MH; University of Rochester Medical Center., Garcea FE; MOSS Rehabilitation Research Institute, Cognitive Neuroscience., Prentiss E; University of Rochester Medical Center., Belkhir R; Department of Psychology, Carnegie Mellon University., Haber SJ; Department of Neurosurgery, University of Rochester Medical Center., Gannon SB; University of Rochester Medical Center., Erickson S; University of Rochester Medical Center., Wright KA; University of Rochester Medical Center., Schmidt MZ; University of Rochester Medical Center., Paulzak A; Department of Neurosurgery, University of Rochester Medical Center., Milano VC; Department of Neurosurgery, University of Rochester Medical Center., Paul DA; Department of Neurosurgery, University of Rochester Medical Center., Foxx K; Department of Neurosurgery, University of Rochester Medical Center., Tivarus M; Department of Imaging Sciences, University of Rochester Medical Center; Department of Neuroscience, University of Rochester Medical Center., Nadler JW; Department of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center., Behr JM; Department of Neurosurgery, University of Rochester Medical Center., Smith SO; Department of Neurosurgery, University of Rochester Medical Center., Li YM; Department of Neurosurgery, University of Rochester Medical Center., Walter K; Department of Neurosurgery, University of Rochester Medical Center., Pilcher WH; Department of Neurosurgery, University of Rochester Medical Center.
Jazyk: angličtina
Zdroj: Journal of visualized experiments : JoVE [J Vis Exp] 2019 Aug 12 (150). Date of Electronic Publication: 2019 Aug 12.
DOI: 10.3791/59592
Abstrakt: The Translational Brain Mapping Program at the University of Rochester is an interdisciplinary effort that integrates cognitive science, neurophysiology, neuroanesthesia, and neurosurgery. Patients who have tumors or epileptogenic tissue in eloquent brain areas are studied preoperatively with functional and structural MRI, and intraoperatively with direct electrical stimulation mapping. Post-operative neural and cognitive outcome measures fuel basic science studies about the factors that mediate good versus poor outcome after surgery, and how brain mapping can be further optimized to ensure the best outcome for future patients. In this article, we describe the interdisciplinary workflow that allows our team to meet the synergistic goals of optimizing patient outcome and advancing scientific understanding of the human brain.
Databáze: MEDLINE