Tuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature.

Autor:	Sari A; Namık Kemal University Faculty of Medicine Department of Orthopedics and Traumatology, Tekirdag, Turkey., Dinçel YM; Namık Kemal University Faculty of Medicine Department of Orthopedics and Traumatology, Tekirdag, Turkey., Erdogdu IH; Adnan Menderes University Faculty of Medicine Department of Pathology, Aydin, Turkey., Sayıner HS; Adiyaman University School of Medicine Department of Department of Infectious Diseases Adiyaman, Turkey., Agir I; Adiyaman University School of Medicine Department of Orthopedics and Traumatology, Adiyaman, Turkey., Çetin MÜ; Namık Kemal University Faculty of Medicine Department of Orthopedics and Traumatology, Tekirdag, Turkey.
Jazyk:	angličtina
Zdroj:	SAGE open medical case reports [SAGE Open Med Case Rep] 2019 Aug 08; Vol. 7, pp. 2050313X19869455. Date of Electronic Publication: 2019 Aug 08 (Print Publication: 2019).
DOI:	10.1177/2050313X19869455
Abstrakt:	Background: Tuberculosis osteomyelitis is rarely seen in the diaphyseal bones. It may be confused with Brodie's abscess due to similar clinical, radiological and laboratory findings. Late diagnosis of the disease causes bone destruction. Tuberculosis osteomyelitis of the bone is a rare condition caused by the Mycobacterium tuberculosis . Its incidence has increased in Western countries in recent years due to HIV infection, increasing elderly population and emerging resistant strains. The slow progress of tuberculous osteomyelitis, due to lack of significant elevations in the laboratory values and changes in the radiographic appearance, often leads to confusion with the subtypes of subacute osteomyelitis, defined as Brodie's abscess. These two low-virulence clinical cases often lead to delays in diagnosis and progressive bone destruction. Case Presentation: We report a 65-year-old male patient who presented to our clinic with pain, swelling and sensitivity in the left leg. Diagnosed with infection in the tibia, the patient had undergone antibiotherapy. However, the patient's symptoms were not resolved and we performed bone curettage and cementation. M. tuberculosis -specific DNA was detected by real-time polymerase chain reaction and the M. tuberculosis complex was produced from the perioperative samples. Conclusion: In conclusion, histopathological examination and polymerase chain reaction are essential before surgery of subacute and chronic osteomyelitis with atypical clinical, laboratory and radiological findings for early diagnosis and accurate treatment. Competing Interests: Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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