Associations between major dietary patterns and biomarkers of endothelial dysfunction in two urban midsized cities in Argentina.

Autor: Defagó MD; Instituto de Investigaciones en Ciencias de la Salud (INICSA), CONICET, Universidad Nacional de Córdoba, Ciudad Universitaria, Córdoba, Argentina; Centro de Excelencia en Salud Cardiovascular para el Cono Sur (CESCAS/SACECH), Instituto de Efectividad Clínica y Sanitaria (IECS), Buenos Aires, Argentina; Escuela de Nutrición, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Edificio Escuelas, Ciudad Universitaria, Córdoba, Argentina. Electronic address: danieladefago@hotmail.com., Elorriaga N; Centro de Excelencia en Salud Cardiovascular para el Cono Sur (CESCAS/SACECH), Instituto de Efectividad Clínica y Sanitaria (IECS), Buenos Aires, Argentina., Eynard AR; Escuela de Nutrición, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Edificio Escuelas, Ciudad Universitaria, Córdoba, Argentina., Poggio R; Centro de Excelencia en Salud Cardiovascular para el Cono Sur (CESCAS/SACECH), Instituto de Efectividad Clínica y Sanitaria (IECS), Buenos Aires, Argentina., Gutiérrez L; Centro de Excelencia en Salud Cardiovascular para el Cono Sur (CESCAS/SACECH), Instituto de Efectividad Clínica y Sanitaria (IECS), Buenos Aires, Argentina., Irazola VE; Centro de Excelencia en Salud Cardiovascular para el Cono Sur (CESCAS/SACECH), Instituto de Efectividad Clínica y Sanitaria (IECS), Buenos Aires, Argentina., Rubinstein AL; Centro de Excelencia en Salud Cardiovascular para el Cono Sur (CESCAS/SACECH), Instituto de Efectividad Clínica y Sanitaria (IECS), Buenos Aires, Argentina.
Jazyk: angličtina
Zdroj: Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition] 2019 Nov - Dec; Vol. 67-68, pp. 110521. Date of Electronic Publication: 2019 Jun 11.
DOI: 10.1016/j.nut.2019.06.002
Abstrakt: Objective: We examined whether dietary patterns (DPS) are associated with endothelial dysfunction (ED) markers in an Argentinian population.
Research Methods & Procedures: The sample in this cross-sectional study was derived from 1,983 subjects from two mid-sized cities in Argentina who were involved in the CESCAS I Study. To define DP, a food-frequency questionnaire was applied. In a subsample randomly selected from the primary cohort, serum concentrations of C-reactive protein (hs-CRP), soluble vascular cell adhesion molecule-1 (sVCAM-1), soluble intercellular adhesion molecule-1 (sICAM-1), and soluble E selectin (sSELE) were determined. Correlations and multiple linear regression models were used to assess the relation between each quartile of DP adherence score and ED markers (Q1 lowest adherence; Q4 highest adherence).
Results: Three DPs were identified: Traditional (TDP), Prudent (PDP), and Convenience and processed (CDP). TDP was characterized by higher intake of refined grains, red meat, whole fat dairy products, vegetable oils, and "mate", a traditional South American infused drink; PDP was characterized by higher intake of vegetables, fruit, low-fat dairy products, whole grains, and legumes; and CDP consisted mainly of processed meat, snacks, pizza, and "empanadas", a stuffed bread served baked or fried. Lower scores (Q2, Q3) in TDP were inversely associated with concentrations of sSELE (P < 0.0001 and P < 0.05, respectively). In PDP, higher scores were inversely associated with hs-CRP, whereas lower scores showed a positive relation with sSELE (P < 0.05). Contrariwise, higher scores in CDP were directly associated with sSELE concentrations (P < 0.05).
Conclusion: Adherence for each DP identified is differentially related to ED markers in the studied population.
(Copyright © 2019 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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