Squamous cell carcinoma as a somatic-type malignancy in an extragonadal immature teratoma of the sinonasal region.

Autor: Sakthivel P; Department of Otorhinolaryngology and Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, 110029, India., Kumar Irugu DV; Department of Otorhinolaryngology and Head Neck Surgery, All India Institute of Medical Sciences, New Delhi, 110029, India., Kakkar A; Department of Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India. Electronic address: aanchalkakkar@gmail.com., Kaur K; Department of Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India., Jain S; Department of Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India., Pramanik R; Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, 110029, India., Biswas A; Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, 110029, India.
Jazyk: angličtina
Zdroj: International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2019 Nov; Vol. 126, pp. 109639. Date of Electronic Publication: 2019 Aug 12.
DOI: 10.1016/j.ijporl.2019.109639
Abstrakt: Somatic-type malignancy arising in a teratoma of the sinonasal region is extremely unusual, creating a diagnostic dilemma. There are no definite guidelines for management of such cases. A 15-year-old male with a maxillary mass was misdiagnosed as angiomyolipoma, maxillary carcinoma, mucoepidermoid carcinoma, and teratocarcinosarcoma, followed by the final diagnosis of squamous cell carcinoma arising in an immature teratoma. He received neoadjuvant chemotherapy, followed by surgery and chemo-radiotherapy, and is disease-free at 21 months. This case highlights the difficulty faced when diagnosing neoplasms unusual to the head and neck region, particularly on small biopsies, and good outcome following appropriate multimodality management.
(Copyright © 2019 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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