| Autor: |
Rimmer EM; Department of Pharmacology, University of Wales College of Medicine, Heath Park, Cardiff, U.K., Milligan NM, Richens A |
| Jazyk: |
angličtina |
| Zdroj: |
Epilepsy research [Epilepsy Res] 1987 Nov-Dec; Vol. 1 (6), pp. 339-46. |
| DOI: |
10.1016/0920-1211(87)90058-1 |
| Abstrakt: |
The acute effect of oral administration of a single dose of vigabatrin, a new antiepileptic drug which acts by irreversible enzyme-activated inhibition of the brain enzyme, GABA-aminotransferase, on the photoconvulsive response in patients with photosensitive epilepsy, was compared with that of the established antiepileptic drug, sodium valproate. Both drugs significantly suppressed the photoconvulsive response in 3 out of 6 subjects. This result was interpreted as further evidence of vigabatrin's potential value in the future treatment of patients with epilepsy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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