| Autor: |
Andreenko GV, Podorol'skaia LV, Serebriakova TN, Liaginskiĭ AV, Egorov BB |
| Jazyk: |
ruština |
| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1988 Oct; Vol. 106 (10), pp. 424-6. |
| Abstrakt: |
The plasminogen activator 960 IU/mg protein activity isolated from cultured fluid of the calf kidney cells was introduced to albino rats (180-200 g) with experimental Heynmann nephritis every day during 4 days. Nephritis caused activation of haemostasis and inhibition of fibrinolysis in the blood. There was increased excretion of the fibrin, fibrinogen degradation products in urine as a results of the local fibrin deposition in diseased kidneys. The fibrinolytic activity of the cortical zone of kidney was markedly decreased. The plasminogen activator, infused to experimental animals, resulted in normalization of the altered indexes. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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