Mathematical modeling reveals alternative JAK inhibitor treatment in myeloproliferative neoplasms.

Autor: Shank K; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.; Penn State College of Medicine, Hershey, Pennsylvania, USA., Dunbar A; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Koppikar P; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Kleppe M; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Teruya-Feldstein J; Department of Pathology, Icahn School of Medicine, Mount Sinai, New York, NY, USA., Csete I; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Bhagwat N; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.; Gerstner Sloan-Kettering Graduate School in Biomedical Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Keller M; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Kilpivaara O; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Michor F; Department of Biostatistics and Computational Biology, Center for Cancer Evolution, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA, and Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA, and Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA., Levine RL; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.; Gerstner Sloan-Kettering Graduate School in Biomedical Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.; Leukemia Service, Memorial Sloan-Kettering Cancer Center, NY, USA., de Vargas Roditi L; Institute of Molecular Cancer Research, University of Zurich, Zurich Switzerland laura.devargasroditi@uzh.ch.
Jazyk: angličtina
Zdroj: Haematologica [Haematologica] 2020 Mar; Vol. 105 (3), pp. e91-e94. Date of Electronic Publication: 2019 Aug 14.
DOI: 10.3324/haematol.2018.203729
Databáze: MEDLINE