Autor: |
Perapoch J; Pediatric Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Vidal R; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Catalonia. Spain.; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain.; Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR).; Biomedical Network Research Centre on Mental Health (CIBERSAM)., Gómez-Lumbreras A; Institut Universitari d'Investigació en Atenció Primària Jordi Gol, Barcelona, Spain., Hermosilla E; Sistema d'Informació per al desenvolupament de la investigació en Atenció Primària, Barcelona, Spain., Riera L; Institut Català de la Salut, Barcelona, Spain., Cortés J; Universitat Politècnica de Catalunya, Barcelona, Spain., Céspedes MC; Pediatric Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Ramos-Quiroga JA; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Catalonia. Spain.; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain.; Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR).; Biomedical Network Research Centre on Mental Health (CIBERSAM)., Morros R; Institut Universitari d'Investigació en Atenció Primària Jordi Gol, Barcelona, Spain.; Deparment of Pharmacology and Therapeutics, Universitat Autònoma de Barcelona, Bellaterra, Spain. |
Abstrakt: |
Objective: To evaluate the association between prematurity (by the gestational week [gw]) and ADHD during childhood. Method: Observational, matched cohort study using data from children born in a tertiary-level hospital (Hospital Universitari Vall d'Hebron, Catalonia, Spain) during 1995-2007 and data from the Information System for the Development of Research in Primary Health Care (SIDIAP database, Catalonia, Spain). Results: Prevalence of ADHD increases as gestational age decreases, 12.7% for those born ≤28 gw, compared to 3.2% for those born after the 37 gw. The risk of developing ADHD in the non-premature children tends to increase as the gw decreases (35-36 gw, hazard ratio [HR] = 1.70, 95% confidence interval [CI] [1.19, 2.44]; 33-34 gw, HR = 3.38, 95% CI [2.08, 5.50]; 29-32 gw, HR = 2.37, 95% CI [1.54, 3.63]; and ≤28 gw, HR = 5.57, 95% CI [2.49, 12.46]) Conclusion: Being born preterm is associated with a risk of developing ADHD, also in late preterm children (35-36 gw). Attention when taking care of these infants regarding their mental health must be made. |