High Prevalence of Syphilis and Inadequate Prenatal Care in Brazilian Pregnant Women: A Cross-Sectional Study.

Autor: Benedetti KCSV; Hospital Universitário de Dourados, Universidade Federal da Grande Dourados-UFGD, Dourados, Brazil.; Laboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Dourados, Brazil., Ribeiro ADDC; Hospital Universitário de Dourados, Universidade Federal da Grande Dourados-UFGD, Dourados, Brazil.; Laboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Dourados, Brazil., Queiroz JHFS; Laboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Dourados, Brazil., Melo ABD; Laboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Dourados, Brazil., Batista RB; Laboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Dourados, Brazil., Delgado FM; Laboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Dourados, Brazil., da Silva KE; Laboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Dourados, Brazil., Croda J; Faculdade de Medicina (FAMED), Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil.; Fundação Oswaldo Cruz (FIOCRUZ), Campo Grande, Brazil., Simionatto S; Laboratório de Pesquisa Em Ciências da Saúde, Universidade Federal da Grande Dourados-UFGD, Dourados, Brazil.
Jazyk: angličtina
Zdroj: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2019 Oct; Vol. 101 (4), pp. 761-766.
DOI: 10.4269/ajtmh.18-0912
Abstrakt: In Brazil, the reported number of syphilis cases among pregnant women has markedly increased. We conducted a cross-sectional study to determine the prevalence of Treponema pallidum infection and associated factors in pregnant women in Dourados, Mato Grosso do Sul, Brazil. Participants voluntarily completed a risk-factor questionnaire and provided blood specimens for unlinked anonymous testing for the presence of antibodies against T. pallidum , the causative agent of syphilis. Data of newborns were obtained from medical records. We performed univariate and multivariate regression analyses to assess associations with syphilis. The seroprevalence of syphilis in pregnant women was 4.4% ( n = 29/661). Twenty-five newborns were seropositive for T. pallidum , and complications due to syphilis were observed in 28% ( n = 7/25). Although 96.5% ( n = 28/29) of women with syphilis received antenatal care, Venereal Disease Research Laboratory tests were performed in the first trimester for 47.6% ( n = 10/21) of women. Women who received treatment in the third trimester (28.6%; n = 6/21) were considered successfully treated at the time of delivery. The use of illicit drugs during pregnancy (odds ratio [OR]: 13.3, 95% CI: 1.9-91.2) and a history of abortion (OR: 3.7, 95% CI: 1.7-8) were associated with syphilis. Our findings highlight that the poor quality of antenatal care services contributes to the high prevalence of syphilis. In addition, there are social and behavioral risk factors associated with syphilis in pregnant women. Future studies are needed to determine limitations of clinical management and control services available to pregnant women with syphilis.
Databáze: MEDLINE