Co-circulation and characterization of novel African arboviruses (genus Ephemerovirus) in cattle, Mayotte island, Indian Ocean, 2017.

Autor: Dacheux L; Institut Pasteur, Unit Lyssavirus Epidemiology and Neuropathology, Paris, France., Dommergues L; GDS Mayotte-Coopérative Agricole des Eleveurs Mahorais, Coconi, France., Chouanibou Y; GDS Mayotte-Coopérative Agricole des Eleveurs Mahorais, Coconi, France., Doméon L; Clinique Vétérinaire de Doméon/Schuler, Mamoudzou, France., Schuler C; Clinique Vétérinaire de Doméon/Schuler, Mamoudzou, France., Bonas S; Institut Pasteur, Unit Lyssavirus Epidemiology and Neuropathology, Paris, France., Luo D; Institut Pasteur, Unit Lyssavirus Epidemiology and Neuropathology, Paris, France.; Wuhan Institute of Virology, CAS Key Laboratory of Special Pathogens and Biosafety, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China., Maufrais C; Institut Pasteur, USR 3756 CNRS, Bioinformatics and Biostatistics Hub, Paris, France., Cetre-Sossah C; CIRAD, UMR ASTRE, Sainte Clotilde, France.; ASTRE, Univ Montpellier (I-MUSE), CIRAD, INRA, Montpellier, France., Cardinale E; CIRAD, UMR ASTRE, Sainte Clotilde, France.; ASTRE, Univ Montpellier (I-MUSE), CIRAD, INRA, Montpellier, France., Bourhy H; Institut Pasteur, Unit Lyssavirus Epidemiology and Neuropathology, Paris, France., Métras R; ASTRE, Univ Montpellier (I-MUSE), CIRAD, INRA, Montpellier, France.; CIRAD, UMR ASTRE, Montpellier, France.
Jazyk: angličtina
Zdroj: Transboundary and emerging diseases [Transbound Emerg Dis] 2019 Nov; Vol. 66 (6), pp. 2601-2604. Date of Electronic Publication: 2019 Aug 27.
DOI: 10.1111/tbed.13323
Abstrakt: Mayotte is an island located in the Mozambique Channel, between Mozambique and Madagascar, in the South Western Indian Ocean region. A severe syndrome of unknown aetiology has been observed seasonally since 2009 in cattle (locally named "cattle flu"), associated with anorexia, nasal discharge, hyperthermia and lameness. We sampled blood from a panel of those severely affected animals at the onset of disease signs and analysed these samples by next-generation sequencing. We first identified the presence of ephemeral bovine fever viruses (BEFV), an arbovirus belonging to the genus Ephemerovirus within the family Rhabdoviridae, thus representing the first published sequences of BEFV viruses of African origin. In addition, we also discovered and genetically characterized a potential new species within the genus Ephemerovirus, called Mavingoni virus (MVGV) from one diseased animal. Finally, both MVGV and BEFV have been identified in cattle from the same herd, evidencing a co-circulation of different ephemeroviruses on the island. The clinical, epidemiological and virological information strongly suggests that these viruses represent the etiological agents of the observed "cattle flu" within this region. This study highlights the importance of the strengthening and harmonizing arboviral surveillance in Mayotte and its neighbouring areas, including Africa mainland, given the importance of the diffusion of infectious diseases (such as BEFV) mediated by animal and human movements in the South Western Indian Ocean area.
(© 2019 The Authors. Transboundary and Emerging Diseases published by Blackwell Verlag GmbH.)
Databáze: MEDLINE
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