Is vitamin-D supplementation not useful in patients at risk of fractures and falls?

Autor: Aguilar Del Rey J; Servicio de Reumatología, Hospital Clínico Virgen de la Victoria, Málaga, Spain., Jódar Gimeno E; Servicio de Endocrinología, Hospital Universitario Quironsalud, Madrid, Spain., Brañas Baztán F; Sección de Geriatría, Hospital Universitario Infanta Leonor, Madrid, Spain., Gómez Alonso C; Servicio de Metabolismo Óseo y Mineral, Hospital Universitario Central de Asturias, Oviedo, Spain., González Lama Y; Servicio de Gastroenterología y Hepatología, Hospital Universitario Puerta de Hierro, Madrid, Spain., Malouf Sierra J; Departamento de Medicina Interna, Unidad de Metabolismo Mineral, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Borrego RS; DIATROS, Clínica de Atención a la Mujer, Barcelona, Spain., Segura de la Morena J; Servicio de Nefrología, Hospital Universitario 12 de Octubre, Madrid, Spain., Suárez Pérez JA; Servicio de Dermatología, Hospital Universitario Virgen de la Victoria, Málaga, Spain., Valdés Y Llorca C; Médico de Familia, Centro de Salud Fuencarral, SERMAS, Madrid, Spain.
Jazyk: angličtina
Zdroj: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2020 Feb; Vol. 36 (2), pp. 93-95. Date of Electronic Publication: 2019 Aug 07.
DOI: 10.1080/09513590.2019.1650346
Abstrakt: To evaluate numerous publications that question the bone and extraosseous benefits of vitamin D diet supplementation based on results, which often transcend to public opinion, but are not well interpreted. This may have negative consequences on compliance of patients under vitamin D supplementation. Critical appraisal of several articles on vitamin D supplementation and its relationship with fractures, falls, cardiovascular diseases, and cancer incidence. Such publications have certain limitations (i.e. patients excluded because of a diagnosis of osteoporosis, or at a higher risk for fractures and falls, or because they have a vitamin D deficiency, etc.), and conclusions and/or subsequent recommendations should be approached with caution. Our research shows that patients with osteoporosis, vitamin D deficiency, and at high risk of fractures and falls should not discontinue vitamin D supplementation (often associated with calcium). It is becoming increasingly evident that patients with hypovitaminosis D are those that gain a maximal benefit from vitamin D supplementation.
Databáze: MEDLINE
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