Chemical and Biological Aspects of Garcinol and Isogarcinol: Recent Developments.
| Autor: | Schobert R; Organic Chemistry Laboratory, University of Bayreuth, 95447, Bayreuth, Germany., Biersack B; Organic Chemistry Laboratory, University of Bayreuth, 95447, Bayreuth, Germany. |
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| Jazyk: | angličtina |
| Zdroj: | Chemistry & biodiversity [Chem Biodivers] 2019 Sep; Vol. 16 (9), pp. e1900366. Date of Electronic Publication: 2019 Aug 30. |
| DOI: | 10.1002/cbdv.201900366 |
| Abstrakt: | The natural polyisoprenylated benzophenone derivatives garcinol and isogarcinol are secondary plant metabolites isolated from various Garcinia species including Garcinia indica. This review takes stock of the recent chemical and biological research into these interesting natural compounds over the last five years. New biological sources and chemical syntheses are discussed followed by new insights into the activity of garcinol and isogarcinol against cancer, pathogenic bacteria, parasite infections and various inflammatory diseases. (© 2019 Wiley-VHCA AG, Zurich, Switzerland.) |
| Databáze: | MEDLINE |
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