Effect of Hemocare Syrup and Hemocare XT Tablets on Hemoglobin levels in iron deficiency anemia among women of reproductive age: A randomized, placebo controlled, open label trial.

Autor:	Vijayakumar TM; Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India., Priyadharshini A; Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India., Ahalya SP; Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India., Lakshmi KS; Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India., Muthunarayanan L; Department of Community Medicine, SRM Medical College Hospital & Research Centre, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India., Rama S; MMC Pharmaceuticals Ltd, Devi Karumariamman Nagar, Valasaravakkam, Chennai, 600 087, Tamil Nadu, India.
Jazyk:	angličtina
Zdroj:	Contemporary clinical trials communications [Contemp Clin Trials Commun] 2019 Jul 23; Vol. 15, pp. 100425. Date of Electronic Publication: 2019 Jul 23 (Print Publication: 2019).
DOI:	10.1016/j.conctc.2019.100425
Abstrakt:	Background: Iron deficiency anemia is one of the important public health problems in developing countries among the women of reproductive age group. Hemocare formulation plays a significant role in Iron deficiency anemia because of its Iron content. The present study aimed to investigate the effect of Hemocare Syrup and Hemocare XT Tablets compared with placebo on Hemoglobin Levels in Iron Deficiency Anemia among Women of Reproductive Age. Methods: A prospective, interventional, randomized, open label, placebo controlled trial has been conducted with 126 patients. Eligible patients randomly received either Placebo 100 mg or Hemocare XT Tablet 100 mg or 10 ml of Hemocare Syrup once daily in the same manner for 4 weeks. Hemoglobin values were documented at the end of 15th day, 21st day and 30th day. Results: The baseline hemoglobin values were compared with each follow up and statistically significant difference was found at the end of 30th day of Hemocare Syrup and Hemocare XT treatment (P < 0.05) but there was no significant difference observed in the placebo group. The study results revealed that 30 days treatment of Hemocare Syrup and Hemocare XT Tablets increases the Hemoglobin levels to 12.46 ± 0.44 g/dl and 12.90 ± 0.98 g/dl from 9.08 ± 2.54 g/dl and 9.68 ± 2.04 g/dl respectively. Conclusion: Hemocare Syrup and Hemocare XT Tablets treatment showed clinically significant improvement in hemoglobin levels from the baseline and placebo group.
Databáze:	MEDLINE
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