Cytomegalovirus distribution and evolution in hominines.

Autor: Murthy S; Division 12 'Measles, Mumps, Rubella and Viruses Affecting Immune-Compromised Patients' Robert Koch Institute, Berlin, Germany., O'Brien K; School of Biomedical and Healthcare Sciences, University of Plymouth, Devon, UK., Agbor A; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany.; African Parks Network, Lonehill, Republic of South Africa., Angedakin S; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany., Arandjelovic M; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany., Ayimisin EA; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany., Bailey E; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany., Bergl RA; North Carolina Zoological Park, Asheboro, USA., Brazzola G; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany., Dieguez P; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany., Eno-Nku M; WWF Cameroon, Yaoundé, Cameroon., Eshuis H; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany., Fruth B; Faculty of Science, School of Natural Sciences and hPsychology, Liverpool John Moores University, Liverpool, UK.; Centre for Research and Conservation, Royal Zoological Society of Antwerp, Antwerp, Belgium., Gillespie TR; Department of Environmental Sciences and Program in Population Biology, Ecology, and Evolutionary Biology, Emory University, Atlanta, USA., Ginath Y; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany., Gray M; International Gorilla Conservation Programme, Kigali, Rwanda.; Batavia Coast Maritime Institute, Geraldton, WA, Australia., Herbinger I; World Wildlife Fund (WWF) Germany, Berlin, Germany., Jones S; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany.; Royal Holloway, University of London, Egham, UK., Kehoe L; Wild Chimpanzee Foundation (WCF), Leipzig, Germany.; Department of Biology, University of Victoria, Victoria, Canada.; Department of Forest and Conservation Sciences, University of British Columbia, Vancouver, Canada., Kühl H; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany.; German Centre for Integrative Biodiversity Research (iDiv), Leipzig, Germany., Kujirakwinja D; Wildlife Conservation Society, NY, USA., Lee K; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany.; School of Human Evolution and Social Change, Arizona State University, Tempe, USA., Madinda NF; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany.; Epidemiology of highly pathogenic microorganisms, Robert Koch Institute, Berlin, Germany., Mitamba G; Wildlife Conservation Society, NY, USA., Muhindo E; Wildlife Conservation Society, NY, USA., Nishuli R; Réserve de Faune à Okapis, Institut Congolais pour la Conservation de la Nature, Kinshasa, Democratic Republic of the Congo., Ormsby LJ; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany., Petrzelkova KJ; Institute of Vertebrate Biology, Academy of Sciences, Brno, Czech Republic.; Department of Pathology and Parasitology, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic.; Biology Centre, Institute of Parasitology, Academy of Sciences of the Czech Republic, Ceske Budejovice, Czech Republic.; Liberec Zoo, Liberec, Czech Republic., Plumptre AJ; Wildlife Conservation Society, NY, USA.; KBA Secretariat, c/o BirdLife International, Cambridge, UK.; Zoology Department, Conservation Science Group, University of Cambridge, Cambridge, UK., Robbins MM; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany., Sommer V; Gashaka Primate Project, Nigeria c/o Department of Anthropology, University College London, London, UK., Ter Heegde M; Epidemiology of highly pathogenic microorganisms, Robert Koch Institute, Berlin, Germany., Todd A; Dzanga Sangha Protected Areas, WWF Central African Republic, Bangui, Central African Republic., Tokunda R; Institute of Vertebrate Biology, Academy of Sciences, Brno, Czech Republic., Wessling E; Max Planck Institute for Evolutionary Anthropology (MPI EVA), Leipzig, Germany.; Dzanga Sangha Protected Areas, WWF Central African Republic, Bangui, Central African Republic., Jarvis MA; School of Biomedical and Healthcare Sciences, University of Plymouth, Devon, UK., Leendertz FH; Epidemiology of highly pathogenic microorganisms, Robert Koch Institute, Berlin, Germany., Ehlers B; Division 12 'Measles, Mumps, Rubella and Viruses Affecting Immune-Compromised Patients' Robert Koch Institute, Berlin, Germany., Calvignac-Spencer S; Epidemiology of highly pathogenic microorganisms, Robert Koch Institute, Berlin, Germany.; Viral Evolution, Robert Koch Institute, Berlin, Germany.
Jazyk: angličtina
Zdroj: Virus evolution [Virus Evol] 2019 Aug 01; Vol. 5 (2), pp. vez015. Date of Electronic Publication: 2019 Aug 01 (Print Publication: 2019).
DOI: 10.1093/ve/vez015
Abstrakt: Herpesviruses are thought to have evolved in very close association with their hosts. This is notably the case for cytomegaloviruses (CMVs; genus Cytomegalovirus ) infecting primates, which exhibit a strong signal of co-divergence with their hosts. Some herpesviruses are however known to have crossed species barriers. Based on a limited sampling of CMV diversity in the hominine (African great ape and human) lineage, we hypothesized that chimpanzees and gorillas might have mutually exchanged CMVs in the past. Here, we performed a comprehensive molecular screening of all 9 African great ape species/subspecies, using 675 fecal samples collected from wild animals. We identified CMVs in eight species/subspecies, notably generating the first CMV sequences from bonobos. We used this extended dataset to test competing hypotheses with various degrees of co-divergence/number of host switches while simultaneously estimating the dates of these events in a Bayesian framework. The model best supported by the data involved the transmission of a gorilla CMV to the panine (chimpanzee and bonobo) lineage and the transmission of a panine CMV to the gorilla lineage prior to the divergence of chimpanzees and bonobos, more than 800,000 years ago. Panine CMVs then co-diverged with their hosts. These results add to a growing body of evidence suggesting that viruses with a double-stranded DNA genome (including other herpesviruses, adenoviruses, and papillomaviruses) often jumped between hominine lineages over the last few million years.
Databáze: MEDLINE