Multi-locus sequence analysis reveals a novel sequence type of Chlamydia trachomatis in Saratov Region, Russia.

Autor: Feodorova VA; Laboratory for Molecular Biology and NanoBiotechnology, Federal Research Center for Virology and Microbiology (FRCViM), Branch in Saratov, Saratov, Russia., Zaitsev SS; Laboratory for Molecular Biology and NanoBiotechnology, Federal Research Center for Virology and Microbiology (FRCViM), Branch in Saratov, Saratov, Russia., Saltykov YV; Laboratory for Molecular Biology and NanoBiotechnology, Federal Research Center for Virology and Microbiology (FRCViM), Branch in Saratov, Saratov, Russia., Ulyanov SS; Laboratory for Molecular Biology and NanoBiotechnology, Federal Research Center for Virology and Microbiology (FRCViM), Branch in Saratov, Saratov, Russia.; Department for Medical Physics, Saratov State University (SSU), Saratov, Russia., Motin VL; Department of Pathology, Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX, USA.
Jazyk: angličtina
Zdroj: New microbes and new infections [New Microbes New Infect] 2019 Jul 03; Vol. 31, pp. 100584. Date of Electronic Publication: 2019 Jul 03 (Print Publication: 2019).
DOI: 10.1016/j.nmni.2019.100584
Abstrakt: Chlamydia trachomatis is the causative agent of a variety of chlamydial infections in humans with a predominantly (up to 80%) asymptomatic course of disease. In this study, a potentially novel C. trachomatis sequence type (ST) was detected in an asymptomatic man who has sex with a man among the nine STs revealed in urogenital swabs from individuals with chlamydia ( n  = 18). Phylogenetically this ST270 clustered separately as a single clade to an ST13-founded group of C. trachomatis strains and differed from the latter by a single allele, hflX . This finding emphasizes the importance of careful investigation of individuals with asymptomatic chlamydia infections.
Databáze: MEDLINE