[Comparative bactericidal kinetics of ciprofloxacin, ofloxacin and pefloxacin alone and in combination against strains of group D Streptococcus].

Autor: Zuccarelli M; Laboratoire de Bactériologie et Biologie cellulaire, Faculté de Pharmacie, Montpellier., Simeon de Buochberg M, Maillols M, Armynot du Chatelet AM, Attisso MA
Jazyk: francouzština
Zdroj: Pathologie-biologie [Pathol Biol (Paris)] 1988 May; Vol. 36 (5), pp. 403-9.
Abstrakt: Killing curves method was used to study bactericidal activity of the three quinolones, alone and in combination with penicillin, amoxicillin, fosfomycin, netilmicin, vancomycin against six isolates of enterococci. Alone, ofloxacin showed the most initial bactericidal effect but ciprofloxacin was the most frequently bactericidal without any regrowth in 24 hours. The combinations with beta-lactams and netilmicin were sometimes synergistic in 24 hours; fosfomycin increased initial bactericidal effect.
Databáze: MEDLINE