Molecular Surveillance of Drug Resistance of Plasmodium falciparum Isolates Imported from Angola in Henan Province, China.
Autor: | Zhou R; Department of Parasite Disease Control and Prevention, Henan Province Center for Disease Control and Prevention, Zhengzhou, People's Republic of China., Yang C; Department of Parasite Disease Control and Prevention, Henan Province Center for Disease Control and Prevention, Zhengzhou, People's Republic of China., Li S; Department of Parasite Disease Control and Prevention, Henan Province Center for Disease Control and Prevention, Zhengzhou, People's Republic of China., Zhao Y; Department of Parasite Disease Control and Prevention, Henan Province Center for Disease Control and Prevention, Zhengzhou, People's Republic of China., Liu Y; Department of Parasite Disease Control and Prevention, Henan Province Center for Disease Control and Prevention, Zhengzhou, People's Republic of China., Qian D; Department of Parasite Disease Control and Prevention, Henan Province Center for Disease Control and Prevention, Zhengzhou, People's Republic of China., Wang H; Department of Parasite Disease Control and Prevention, Henan Province Center for Disease Control and Prevention, Zhengzhou, People's Republic of China., Lu D; Department of Parasite Disease Control and Prevention, Henan Province Center for Disease Control and Prevention, Zhengzhou, People's Republic of China., Zhang H; Department of Parasite Disease Control and Prevention, Henan Province Center for Disease Control and Prevention, Zhengzhou, People's Republic of China zhwei69@163.com huangfang@nipd.chinacdc.com., Huang F; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People's Republic of China zhwei69@163.com huangfang@nipd.chinacdc.com. |
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Jazyk: | angličtina |
Zdroj: | Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2019 Sep 23; Vol. 63 (10). Date of Electronic Publication: 2019 Sep 23 (Print Publication: 2019). |
DOI: | 10.1128/AAC.00552-19 |
Abstrakt: | Angola was the main origin country for the imported malaria in Henan Province, China. Antimalarial drug resistance has posed a threat to the control and elimination of malaria. Several molecular markers were confirmed to be associated with the antimalarial drug resistance, such as pfcrt , pfmdr1 , pfdhfr , pfdhps , and K13. This study evaluated the drug resistance of the 180 imported Plasmodium falciparum isolates from Angola via nested PCR using Sanger sequencing. The prevalences of pfcrt C (Copyright © 2019 American Society for Microbiology.) |
Databáze: | MEDLINE |
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