Multifunctional one-dimensional polymeric nanostructures for drug delivery and biosensor applications.

Autor: Sayin S; Materials Science and Nano Engineering, Faculty of Engineering and Natural Sciences, Sabanci University, 34956 Istanbul, Turkey., Ozdemir E, Acar E, Ince GO
Jazyk: angličtina
Zdroj: Nanotechnology [Nanotechnology] 2019 Oct 11; Vol. 30 (41), pp. 412001. Date of Electronic Publication: 2019 Jul 26.
DOI: 10.1088/1361-6528/ab2e2c
Abstrakt: Advances in nanotechnology in the last decades have paved the way for significant achievements in diagnosis and treatment of various diseases. Different types of functional nanostructures have been explored and utilized as tools for addressing the challenges in detection or treatment of diseases. In particular, one-dimensional nanostructures hold great promise in theranostic applications due to their increased surface area-to-volume ratios, which allow better targeting, increased loading capacity and improved sensitivity to biomolecules. Stable polymeric nanostructures that are stimuli-responsive, biocompatible and biodegradable are especially preferred for bioapplications. In this review, different synthesis techniques of polymeric one-dimensional nanostructures are explored and functionalization methods of these nanostructures for specific applications are explained. Biosensing and drug delibiovery applications of these nanostructures are presented in detail.
Databáze: MEDLINE