Quality of life, risk behaviors and depression among carriers of hepatitis C virus and human T-cell lymphotropic virus type 1: a comparative study.

Autor:	Henrique-Araújo R; Federal University of Bahia, Institute of Health Sciences, Postgraduate Program in Interactive Processes of Organs and Systems, Salvador, BA, Brazil; Nova Esperança Medical School, João Pessoa, PB, Brazil; Hospital Complex of Infectious Diseases Clementino Fraga, João Pessoa, PB, Brazil. Electronic address: ricardohsaraujo@gmail.com., Quarantini LC; Federal University of Bahia, Postgraduate Program in Medicine and Health, Salvador, BA, Brazil; Federal University of Bahia, Psychiatry Service, University Hospital (Com-HUPES), Salvador, BA, Brazil., Caribé AC; Federal University of Bahia, Psychiatry Service, University Hospital (Com-HUPES), Salvador, BA, Brazil., Argolo FC; Federal University of São Paulo, Postgraduate Program in Psychiatry and Medical Psychology, São Paulo, SP, Brazil., Jesus-Nunes AP; Federal University of Bahia, Postgraduate Program in Medicine and Health, Salvador, BA, Brazil; Federal University of Bahia, Psychiatry Service, University Hospital (Com-HUPES), Salvador, BA, Brazil., Morais-de-Jesus M; Federal University of Bahia, Postgraduate Program in Medicine and Health, Salvador, BA, Brazil; Federal University of Bahia, Psychiatry Service, University Hospital (Com-HUPES), Salvador, BA, Brazil., Dantas-Duarte A; Federal University of Bahia, Psychiatry Service, University Hospital (Com-HUPES), Salvador, BA, Brazil., Moreira TM; Federal University of Bahia, Psychiatry Service, University Hospital (Com-HUPES), Salvador, BA, Brazil., Oliveira IR; Federal University of Bahia, Institute of Health Sciences, Postgraduate Program in Interactive Processes of Organs and Systems, Salvador, BA, Brazil; Federal University of Bahia, Postgraduate Program in Medicine and Health, Salvador, BA, Brazil.
Jazyk:	angličtina
Zdroj:	The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases [Braz J Infect Dis] 2019 Jul - Aug; Vol. 23 (4), pp. 224-230. Date of Electronic Publication: 2019 Jul 22.
DOI:	10.1016/j.bjid.2019.06.013
Abstrakt:	Human T-cell lymphotropic virus type 1 (HTLV-1) has low prevalence rates, but is endemic in some regions of the world. It is usually a chronic asymptomatic infection, but it can be associated with serious neurologic and urinary conditions. Hepatitis C virus (HCV) is broadly spread out worldwide. The majority of these infections have a chronic course that may progress to cirrhosis and hepatocellular carcinoma. Objectives: To compare sociodemographic and mental health (risk behaviors, depression, and suicide) aspects, and quality of life among patients with HCV or HTLV-1. Methods: Observational, comparative and cross-sectional study involving outpatients with HCV or HLTV-1 infection. Sociodemographic characteristics, risk behaviors and quality of life were assessed through the questionnaires Mini International Neuropsychiatric Interview - MINI Plus (depression and suicide) and Medical Outcomes Study 36-Item Short-Form Health Survey (quality of life). Univariate and multivariate statistical analyses (hierarchical logistic regression) were conducted. Results: 143 individuals with HCV and 113 individuals with HTLV-1 infection were included. Males were predominant in the HCV group (68.8%) and females in the HTLV-1 group (71.7%). The frequency of risk behaviors (sexual and drug use) was greater in those with HCV (p < 0.05). A past depressive episode was more common in the HTLV-1 group (p = 0.037). Quality of life was significantly worse in the physical functioning, vitality, mental health, and social functioning domains in those with HTLV-1 (p < 0.05). HTLV-1 infection remained independently associated with worse quality of life in multivariate analysis. Conclusions: Risk behaviors are frequent among those infected with HCV. Additionally, despite HTLV-1 being considered an infection with low morbidity, issues related to mental health (depressive episode) and decreased quality of life are relevant. (Copyright © 2019 Sociedade Brasileira de Infectologia. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu