Successful palliative peptide receptor radionuclide therapy for impending compression of vena cava due to unresectable liver metastasis of neuroendocrine tumor.

Autor: Ataeinia B; Department of Nuclear Medicine, University Hospital RWTH Aachen, Aachen, Germany.; Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran., Loberg C; Department of Nuclear Medicine, University Hospital RWTH Aachen, Aachen, Germany., Kravets H; Department of Nuclear Medicine, University Hospital RWTH Aachen, Aachen, Germany., Beheshti M; Department of Nuclear Medicine, University Hospital RWTH Aachen, Aachen, Germany., von Mallek D; Department of Nuclear Medicine, University Hospital RWTH Aachen, Aachen, Germany., Mottaghy FM; Department of Nuclear Medicine, University Hospital RWTH Aachen, Aachen, Germany.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands., Heinzel A; Department of Nuclear Medicine, University Hospital RWTH Aachen, Aachen, Germany.
Jazyk: angličtina
Zdroj: EXCLI journal [EXCLI J] 2019 May 21; Vol. 18, pp. 273-276. Date of Electronic Publication: 2019 May 21 (Print Publication: 2019).
DOI: 10.17179/excli2019-1220
Abstrakt: We present the case of a 77 year old male patient with metastatic pancreatic neuroendocrine tumor (NET). The patient was initially treated by extensive surgical resection that however, led to severe complications with delayed recovery. During follow-up, a number of new liver metastases were detected, one of which was in segment I with impending compression of the inferior vena cava. Due to age and general condition of the patient, instead of further surgical treatment, the patient received four cycles of 177 Lu-DOTATOC resulting in an overall partial response with successful tumor reduction in liver segment I, resolving an impending compression of vena cava.
Databáze: MEDLINE