Effects of vitamin D supplementation along with endurance physical activity on lipid profile in metabolic syndrome patients: A randomized controlled trial.

Autor: Farag HAM; Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Science, International Campus (TUMS- IC), Tehran, Iran; Halabja Technical Institute, Sulaimani Polytechnic University, Kurdistan, Iraq. Electronic address: halgord.farag@spu.edu.iq., Hosseinzadeh-Attar MJ; Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Science, International Campus (TUMS- IC), Tehran, Iran. Electronic address: Hosseinzadeh.mdphd@yahoo.com., Muhammad BA; Halabja Technical Institute, Sulaimani Polytechnic University, Kurdistan, Iraq. Electronic address: cmbiology@gmail.com., Esmaillzadeh A; Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: a.esmaillzadeh@gmail.com., Hamid El Bilbeisi A; Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Science, International Campus (TUMS- IC), Tehran, Iran. Electronic address: abed_az@hotmail.com.
Jazyk: angličtina
Zdroj: Diabetes & metabolic syndrome [Diabetes Metab Syndr] 2019 Mar - Apr; Vol. 13 (2), pp. 1093-1098. Date of Electronic Publication: 2019 Jan 22.
DOI: 10.1016/j.dsx.2019.01.029
Abstrakt: Background and Objectives: This study was conducted to determine the effects of vitamin D supplementation along with endurance physical activity on lipid profile among metabolic syndrome patients.
Materials and Methods: In a parallel randomized placebo controlled trial, 70 metabolic syndrome patients, were randomly assigned into three groups. Biochemical tests were assessed as baseline and after 12 weeks of intervention. Statistical analysis was performed using SPSS version 20.
Results: The mean vitamin D levels was increased significantly in both vitamin D and vitamin D plus physical activity groups (P value < 0.05). No significant change was observed in the placebo group. Additionally, there was a significant decrease in total cholesterol and LDL-C in vitamin D plus physical activity group (P value < 0.05). No significant differences in changes of triglycerides and HDL-C among the three groups (P value > 0.05). While, in vitamin D group a decreased in total cholesterol, HDL-C, LDL-C and increase in triglycerides were observed, but did not reach a statistically significant.
Conclusion: Daily supplementation of vitamin D for 12 weeks, along with moderate endurance physical activity, significantly increase vitamin D concentration and induce a significant reduction in lipid profile in metabolic syndrome patients.
(Copyright © 2019 Diabetes India. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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