Linear periodization of strength training in blocks attenuates hypertension and diastolic dysfunction with normalization of myocardial collagen content in spontaneously hypertensive rats.

Autor:	Perilhão MS; Department of Nephrology, Federal University of São Paulo Department of Physical Education, Laboratory of Morphoquantitative Studies and Immunohistochemistry, São Judas Tadeu University Department of Cardiology, Federal University of São Paulo, São Paulo-SP Department of Physical Education, Federal University of São Paulo, Campus Baixada Santista, Santos-SP Laboratory of Experimental Physiology and Biochemistry of the Center of Physical Education and Sports, Federal University of Espirito Santo, Vitoria-ES, Brazil., Krause Neto W, da Silva AA, Alves LLS, Antonio EL, Medeiros A, Rica RL, Serra AJ, Tucci PJF, Bocalini DS
Jazyk:	angličtina
Zdroj:	Journal of hypertension [J Hypertens] 2020 Jan; Vol. 38 (1), pp. 73-81.
DOI:	10.1097/HJH.0000000000002188
Abstrakt:	Background and Method: This study evaluated the effects of a linear block strength training programme on the parameters of cardiac remodelling in spontaneously hypertensive rats. Thirty-nine rats were equally distributed in four groups: normotensive sedentary, normotensive trained, hypertensive sedentary and hypertensive trained. The strength training protocol was organized in three mesocycles of 4 weeks, with an increase in the training load organized in a linear fashion for each block, considering the weight established in the maximum loaded load test. The following parameters were evaluated: ventricular function assessed by echocardiogram, caudal blood pressure, ventricular haemodynamics and cardiac masses. Two-way analysis of variance was used to determine the differences between the group and time. Results: After 12 weeks of training, the hypertensive trained group presented the following results: increased muscle strength, reduced blood pressure, reduced heart rate, isovolumetric relaxation time and total collagen content, with increased cardiac function, without promoting changes in the mass and nuclear volume of cardiomyocytes. Also, blood pressure reduction seems to be associated with both muscle strength adjustments and total load progress. Conclusion: The findings of this study showed that the training programme carried out attenuated systemic arterial pressure and preserved the ventricular function of spontaneously hypertensive rats without cardiac mass change.
Databáze:	MEDLINE
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