Prothrombin Time
| Autor: | Yang R; American University/ Kern Medical, Moosavi L; Kern Medical Center |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | 2021 Jan. |
| Abstrakt: | Prothrombin time (PT) is one of several blood tests routinely used in clinical practice to evaluate the coagulation status of patients. More specifically, PT is used to evaluate the extrinsic and common pathways of coagulation, which would detect deficiencies of factors II, V, VII, and X, and low fibrinogen concentrations.[1][2] PT measures the time, in seconds, for plasma to clot after adding thromboplastin, (a mixture of tissue factor, calcium, and phospholipid) to a patient's plasma sample.[1] Many different preparations of thromboplastin reagents are available which can give different PT results even when using the same plasma. Due to this variability, the World Health Organization (WHO) introduced the international normalized ratio (INR) and has become the standard reporting format for PT results.[3][4] The INR represents to the ratio of the patient's PT divided by a control PT value obtained by using an international reference thromboplastin reagent developed by the WHO.[1][3] (Copyright © 2021, StatPearls Publishing LLC.) |
| Databáze: | MEDLINE |
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