Epitope-imprinted mesoporous silica nanoparticles for specific recognition of tyrosine phosphorylation.

Autor: Zhang G; Key Laboratory Molecular Enzymology and Engineering, the Ministry of Education, National Engineering Laboratory of AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130023, China. lianghaihu@jlu.edu.cn., Jiang L, Zhou J, Hu L, Feng S
Jazyk: angličtina
Zdroj: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2019 Aug 15; Vol. 55 (67), pp. 9927-9930.
DOI: 10.1039/c9cc03950c
Abstrakt: Tyrosine phosphorylation regulates the upstream signaling pathway but accounts for less than 0.1% of total phosphorylation in human cells. Herein, molecularly imprinted mesoporous materials were first synthesized to recognize the phosphorylated tyrosine residue from other phosphorylated residues.
Databáze: MEDLINE