Feline immunodeficiency virus in Northern Ceará, Brazil.

Autor:	Teixeira BM; UNINTA - University Center INTA, Sobral, CE, Brazil., Taniwaki SA; Departaments of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, SP, Brazil., Menezes PMM; UNINTA - University Center INTA, Sobral, CE, Brazil., Rodrigues AKPP; UNINTA - University Center INTA, Sobral, CE, Brazil., Mouta AN; UNINTA - University Center INTA, Sobral, CE, Brazil., Arcebispo TLM; Department of Preventive Veterinary Medicine, Veterinary School, Federal University of Minas Gerais (EV-UFMG), Belo Horizonte, MG, Brasil., Braz GF; UNINTA - University Center INTA, Sobral, CE, Brazil., da Cruz JCM; UNINTA - University Center INTA, Sobral, CE, Brazil., Brandão PE; Departaments of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, SP, Brazil., Heinemann MB; Departaments of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, SP, Brazil., Silva MX; Department of Preventive Veterinary Medicine, Veterinary School, Federal University of Minas Gerais (EV-UFMG), Belo Horizonte, MG, Brasil., Hosie MJ; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK.
Jazyk:	angličtina
Zdroj:	JFMS open reports [JFMS Open Rep] 2019 Jul 08; Vol. 5 (2), pp. 2055116919859112. Date of Electronic Publication: 2019 Jul 08 (Print Publication: 2019).
DOI:	10.1177/2055116919859112
Abstrakt:	Objectives: The objectives of this study were to confirm the prevalence of feline immunodeficiency virus (FIV) infection in domestic cats in the region north of Ceará, Brazil, and to determine the factors associated with infection and the major circulating subtypes of the virus in this area. Methods: Samples from 148 cats were collected and tested using anti-FIV antibody screening, with confirmation of positive results by PCR. Univariate analysis was performed considering the epidemiological characteristics and FIV status. Sequencing and phylogenetic analysis of the gag and pol genes were performed to confirm the FIV subtype. Results: Nine cats (6.1%) tested positive for FIV - one female (0.7%) and eight males (5.4%). Male cats were significantly more likely to be infected ( P <0.05). Phylogenetic analysis of gag and pol gene sequences indicated that the FIV isolates circulating in the study area belonged to subtype B. Conclusions and Relevance: In this study, we demonstrated a low prevalence for FIV in the northwest of Ceará, north-eastern Brazil. Male sex is a significant risk factor for FIV infection and the best predictive factor for FIV status. All isolates examined in this study clustered within subtype B, which is the predominant subtype in Brazil. This is the first report of genetic characterization of FIV in the state of Ceará, Brazil. Competing Interests: Conflict of interest: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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