Prevalence of HIV, Hepatitis B and C Virus Co-infections among Iranian High-Risk Groups: A Systematic Review and Meta-Analysis.

Autor: Hashiani AA; Department of Epidemiology, Arak University of Medical Sciences, Arak, Iran and Traditional and Complementary Medicine Research Center, Arak University of Medical Sciences, Arak, Iran., Sadeghi F; Infectious Diseases & Tropical Medicine Research Center, Babol University of Medical Sciences, Babol, Iran., Ayubi E; Department of Community Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran., Rezaeian S; Research Center for Environmental Determinants of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran., Moradi Y; Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran., Mansori K; Department of Epidemiology and Biostatistics, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran., Gholamaliei B; Department of Public Health, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran., Mohammadbeigi A; Research Center of Gastroenterology and Hepatology, Qom University of Medical Sciences, Qom, Iran., Khazaei S; Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran.
Jazyk: angličtina
Zdroj: The Malaysian journal of medical sciences : MJMS [Malays J Med Sci] 2019 May; Vol. 26 (3), pp. 37-48. Date of Electronic Publication: 2019 Jun 28.
DOI: 10.21315/mjms2019.26.3.3
Abstrakt: Co-infection with hepatitis B and C among HIV infected patients are prevalent among high-risk populations. This meta-analysis aimed to estimate the prevalence of HIV, HCV and HBV co-infections among high-risk populations in Iran. We systematically searched the national and international electronic databases until 2016. The primary outcome was the prevalence of HIV, HBV, HCV and HIV co-infections in different high-risk populations in Iran. All English and Persian studies conducted on Iranian high-risk groups were included in the study. The review was reported based on PRISMA guidelines and data were analysed at 95% confidence level using random effect models. Overall, 916 relevant papers were recognised and 14 articles were included in the meta-analysis. The pooled estimates of HBV/HCV, HCV/HIV, HBV/HIV and HBV/HCV/HIV were 1.3% (95%CI: 0.5-2.1), 16.3% (95%CI: 1.1-31.6), 0.5% (95%CI: 0-1.4) and 0.5% (95%CI: 0.2-0.8), respectively. Based on subgroup analysis, there was a higher proportion of all co-infections from the years 2010-2016 as compared to that of the years 2003-2009. Our results highlighted that HCV/HIV co-infection in Iranian high-risk groups including injection drug users (IDUs) and prisoners is common. In addition, the increasing trend of coinfections should be considered alarming for policymakers.
Competing Interests: Conflict of Interest None.
Databáze: MEDLINE
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