Incentives for Viral Suppression in People Living with HIV: A Randomized Clinical Trial.

Autor: Silverman K; Department of Psychiatry and Behavioral Sciences, Center for Learning and Health, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Suite 350 East, Baltimore, MD, 21224, USA. ksilverm@jhmi.edu., Holtyn AF; Department of Psychiatry and Behavioral Sciences, Center for Learning and Health, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Suite 350 East, Baltimore, MD, 21224, USA., Rodewald AM; Department of Psychiatry and Behavioral Sciences, Center for Learning and Health, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Suite 350 East, Baltimore, MD, 21224, USA., Siliciano RF; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Jarvis BP; Department of Psychiatry and Behavioral Sciences, Center for Learning and Health, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Suite 350 East, Baltimore, MD, 21224, USA.; Knowesis, LLC, Fairfax, VA, USA., Subramaniam S; Department of Psychiatry and Behavioral Sciences, Center for Learning and Health, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Suite 350 East, Baltimore, MD, 21224, USA.; Department of Psychology and Child Development, California State University Stanislaus, Turlock, CA, USA., Leoutsakos JM; Department of Psychiatry and Behavioral Sciences, Center for Learning and Health, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Suite 350 East, Baltimore, MD, 21224, USA., Getty CA; Department of Psychiatry and Behavioral Sciences, Center for Learning and Health, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Suite 350 East, Baltimore, MD, 21224, USA.; Addictions Department, Kings College, London, England, UK., Ruhs S; Chase Brexton Health Care, Baltimore, MD, USA., Marzinke MA; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Fingerhood M; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jazyk: angličtina
Zdroj: AIDS and behavior [AIDS Behav] 2019 Sep; Vol. 23 (9), pp. 2337-2346.
DOI: 10.1007/s10461-019-02592-8
Abstrakt: The HIV/AIDS epidemic can be eliminated if 73% of people living with HIV take antiretroviral medications and achieve undetectable viral loads. This study assessed the effects of financial incentives in suppressing viral load. People living with HIV with detectable viral loads (N = 102) were randomly assigned to Usual Care or Incentive groups. Incentive participants earned up to $10 per day for 2 years for providing blood samples that showed either reduced or undetectable viral loads. This report presents data on the 1st year after random assignment. Incentive participants provided more (adjusted OR = 15.6, CI 4.2-58.8, p < 0.001) blood samples at 3-month assessments with undetectable viral load (72.1%) than usual care control participants (39.0%). We collected most blood samples. The study showed that incentives can substantially increase undetectable viral loads in people living with HIV. Financial incentives for suppressed viral loads could contribute to the eradication of the HIV/AIDS epidemic.
Databáze: MEDLINE
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