Effect of an educational intervention on the number potential drug-drug interactions.

Autor:	Mussina AZ; Department of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, Abulhair Khan Avenue, 21-1-30, Aktobe 030020, Kazakhstan., Smagulova GA; Department of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, Alia Moldagulova Avenue, 47-84, Aktobe 030000, Kazakhstan., Veklenko GV; Department of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, Eset Batyr Street, 109-1-8, Aktobe 030000, Kazakhstan., Tleumagambetova BB; Department of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, Almaty District, Residential Massif Kargaly, 2 Mikroroyon, 16v - 230, Aktobe 030000, Kazakhstan., Seitmaganbetova NA; Department of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, 131g Bokenbay Batyr Street - 126, Aktobe 030000, Kazakhstan., Zhaubatyrova AA; Department of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, Novatorov lane 1, Aktobe 030012, Kazakhstan., Zhamaliyeva LM; Center for Family Medicine and Primary Care Research, West Kazakhstan Marat Ospanov State Medical University, Alia Moldagulova Avenue, 11B - 120, Aktobe 030019, Kazakhstan.
Jazyk:	angličtina
Zdroj:	Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society [Saudi Pharm J] 2019 Jul; Vol. 27 (5), pp. 717-723. Date of Electronic Publication: 2019 Apr 08.
DOI:	10.1016/j.jsps.2019.04.007
Abstrakt:	Background: The objective of this study was to evaluate effect of an Educational intervention on the number Potential Drug-Drug Interactions in the Emergency Hospital. Methods: The prevalence and structure of Major Drug-Drug Interactions at Emergency care Hospitals of Aktobe, Uralsk, Atyrau cities (Kazakhstan) were studied (pharmacoepidemiological, cross-sectional study). Educational interventions were developed and implemented to improve pharmacotherapy in the Cardiology Department of the Aktobe Emergency Hospital, followed by an assessment of their effect. Results: The effect of educational interventions was revealed, which led to a significant decrease in the indicators of drug interactions of the Major Drug-Drug Interactions by 18.2% (OR: 0.45; 95% CI, 0.25-to-0.82) in the cardiological patients of the Emergency Care Hospital of Aktobe city compared to the Regional Cardiology Center of Uralsk. Conclusion: The implementation of educational pharmacotherapy programs decreased the number of clinically significant drug interactions in the Cardiology Department of Emergency Hospitals.
Databáze:	MEDLINE
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