Pickering emulsions: Preparation processes, key parameters governing their properties and potential for pharmaceutical applications.

Autor: Albert C; Institut Galien Paris-Sud, CNRS UMR 8612, Univ Paris-Sud, Université Paris-Saclay, Faculté de Pharmacie, 5 rue J.B. Clément, 92296 Châtenay-Malabry, France., Beladjine M; Institut Galien Paris-Sud, CNRS UMR 8612, Univ Paris-Sud, Université Paris-Saclay, Faculté de Pharmacie, 5 rue J.B. Clément, 92296 Châtenay-Malabry, France., Tsapis N; Institut Galien Paris-Sud, CNRS UMR 8612, Univ Paris-Sud, Université Paris-Saclay, Faculté de Pharmacie, 5 rue J.B. Clément, 92296 Châtenay-Malabry, France., Fattal E; Institut Galien Paris-Sud, CNRS UMR 8612, Univ Paris-Sud, Université Paris-Saclay, Faculté de Pharmacie, 5 rue J.B. Clément, 92296 Châtenay-Malabry, France., Agnely F; Institut Galien Paris-Sud, CNRS UMR 8612, Univ Paris-Sud, Université Paris-Saclay, Faculté de Pharmacie, 5 rue J.B. Clément, 92296 Châtenay-Malabry, France., Huang N; Institut Galien Paris-Sud, CNRS UMR 8612, Univ Paris-Sud, Université Paris-Saclay, Faculté de Pharmacie, 5 rue J.B. Clément, 92296 Châtenay-Malabry, France. Electronic address: nicolas.huang@u-psud.fr.
Jazyk: angličtina
Zdroj: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2019 Sep 10; Vol. 309, pp. 302-332. Date of Electronic Publication: 2019 Jul 08.
DOI: 10.1016/j.jconrel.2019.07.003
Abstrakt: An increased interest in Pickering emulsions has emerged over the last 15 years, mainly related to their very attractive properties compared to regular emulsions, namely their excellent stability and their numerous possible applications. In this review, after detailing the interest of Pickering emulsions, their main preparation processes are presented and their advantages and disadvantages discussed. In the third part, the key parameters that govern Pickering emulsions type, droplet size and stability are analyzed. Finally, the interest and the potential of Pickering emulsions for pharmaceutical applications are exposed and discussed, taking all the administration routes into consideration and focusing on organic particles.
(Copyright © 2019 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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