Leiomyomatosis peritonealis disseminata: a rare disease with a difficult diagnosis.
| Autor: | Martins Jordão D; Serviço de Cirurgia Geral, Instituto Portugues de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal., Santos Pereira J; Serviço de Cirurgia Geral, Instituto Portugues de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal., Furtado E; Serviço de Cirurgia Geral, Centro Hospitalar e Universitario de Coimbra EPE Coimbra Portugal, Coimbra, Portugal., Ferrão IC; Serviço de Cirurgia Geral, Instituto Portugues de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal. |
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| Jazyk: | angličtina |
| Zdroj: | BMJ case reports [BMJ Case Rep] 2019 Jul 08; Vol. 12 (7). Date of Electronic Publication: 2019 Jul 08. |
| DOI: | 10.1136/bcr-2019-229564 |
| Abstrakt: | Leiomyomatosis peritonealis disseminata (LPD) is a rare condition, characterised by the proliferation of peritoneal smooth muscle nodules. LPD is a benign disease with a low rate of malignant degeneration. We describe the case of a 46-year-old, asymptomatic, woman presenting with a mass on the left renal hilum, identified by ultrasound. A CT scan showed three nodules near the left kidney, a mass anterior to the vena cava and bilateral iliac nodules. Biopsy revealed a mesenchymal low-grade tumour. The patient underwent a left nephrectomy and excision of the other masses. The histological diagnosis revealed smooth muscle nodular proliferation with no malignant features, compatible with LPD. The differential diagnosis between LPD and metastatic leiomyosarcoma is sometimes very difficult because they are clinically very similar and even on histology the diagnosis can be tricky. Treatment is conservative in most cases, with surgical excision reserved for high-risk patients. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.) |
| Databáze: | MEDLINE |
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