Prescribing pattern of statins for primary prevention of cardiovascular diseases in patients with type 2 diabetes: insights from Ethiopia.

Autor: Demoz GT; School of Pharmacy, College of Health Sciences, Aksum University, PO.Box: 298, Aksum, Ethiopia. gebretekl@gmail.com., Wahdey S; School of Public Health, Mekelle University, Mekelle, Ethiopia., Kasahun GG; School of Pharmacy, College of Health Sciences, Aksum University, PO.Box: 298, Aksum, Ethiopia., Hagazy K; School of Pharmacy, College of Health Sciences, Aksum University, PO.Box: 298, Aksum, Ethiopia., Kinfe DG; School of Medicine, Aksum University, Aksum, Ethiopia., Tasew H; Nursing School, Aksum University, Aksum, Ethiopia., Bahrey D; Nursing School, Aksum University, Aksum, Ethiopia., Niriayo YL; School of Pharmacy, Mekelle University, Mekelle, Ethiopia.
Jazyk: angličtina
Zdroj: BMC research notes [BMC Res Notes] 2019 Jul 09; Vol. 12 (1), pp. 386. Date of Electronic Publication: 2019 Jul 09.
DOI: 10.1186/s13104-019-4423-9
Abstrakt: Objective: Although most clinical practice guidelines endorsed statin use in type 2 diabetes (T2D) patients for reducing cardiovascular diseases (CVD), little is known about statin utilization in case of Ethiopia. Hence, this study was aimed to evaluate prescribing pattern of statins for primary prevention of CVD in T2D patients. A retrospective study conducted in T2D patients with the age group of 40-75 years. Prescriptions were audited for details of statin use and dose intensity. Descriptive analysis was performed using SPSS version 22.0.
Results: We included a total of 323 study subjects. Of those, 55.7% study subjects were found to be received statin for their primary prevention of CVD. Commonly prescribed type of statins was simvastatin (37.2%), atorvastatin (32.8%) and rosuvastatin (15.6%). Low, moderate and high intensive dose of statins were prescribed in 27.8%, 46.1%, and 26.1%, respectively. Of those subjects received statin, 60.6% had on target cholesterol level. Overall, a significant percentage of subjects did not receive their recommended statin for primary prevention of CVD which is below the guidelines' recommendation. Therefore, adherence to guidelines may help to promote the use of statins for primary prevention of CVD in T2D and advance interventions to improve statin prescribing should be considered.
Databáze: MEDLINE
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