Management of Multiple Secreting Paragangliomas in a Succinate Dehydrogenase Subunit D (SDHD) Variant Carrier.

Autor:	Rijken JA; Department of Otolaryngology/Head and Neck Surgery, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, the Netherlands. Electronic address: johannesrijken@hotmail.com., de Vos B; Department of Otolaryngology/Head and Neck Surgery, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, the Netherlands., Leemans CR; Department of Otolaryngology/Head and Neck Surgery, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, the Netherlands., Zwezerijnen GJCB; Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, the Netherlands., de Graaf P; Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, the Netherlands., Hensen EF; Department of Otolaryngology/Head and Neck Surgery, Leiden University Medical Center, Leiden, the Netherlands., Dreijerink KMA; Department of Endocrinology, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, the Netherlands., Dickhoff C; Department of Surgery, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands., Symersky P; Department of Cardiothoracic Surgery, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, the Netherlands.
Jazyk:	angličtina
Zdroj:	The Annals of thoracic surgery [Ann Thorac Surg] 2020 Feb; Vol. 109 (2), pp. e87-e90. Date of Electronic Publication: 2019 Jul 04.
DOI:	10.1016/j.athoracsur.2019.05.037
Abstrakt:	Management of functional intrathoracic sympathetic paragangliomas in succinate dehydrogenase subunit D (SDHD) mutation carriers is challenging, and there is no uniform guideline for treatment to date. The risks of potential malignant behavior and long-term cardiovascular morbidity have to be weighed against the risks of treatment complications. We report the multidisciplinary and shared decision-making approach that resulted in successful surgical removal of 3 paragangliomas in a SDHD mutation carrier. (Copyright © 2020 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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