Giant congenital melanocytic nevus associated with lipoma in an Indian man.

Autor:	Agarwal A; Pathology, King George's Medical University, Lucknow, UP, India., Dhameja N; Pathology, Banaras Hindu University Institute of Medical Sciences, Varanasi, UP, India., Ghosh Kar A; Pathology, Banaras Hindu University Institute of Medical Sciences, Varanasi, UP, India.
Jazyk:	angličtina
Zdroj:	BMJ case reports [BMJ Case Rep] 2019 Jul 03; Vol. 12 (7). Date of Electronic Publication: 2019 Jul 03.
DOI:	10.1136/bcr-2018-228688
Abstrakt:	Congenital melanocytic nevus is a inborn melanocytic proliferation either present since birth or soon afterward and shows characteristic histopathological features comprising proliferation of benign melanocytes and extension of nevus cells into the deep reticular dermis and subcutis. We report the case of a 35-year-old male patient who presented with a progressively enlarging soft tissue mass in bilateral flank region. High-resolution ultrasound imaging showed multiple lipomatous masses within the soft tissues on the either flank region. Subsequent excision of the soft tissue mass showed a well-circumscribed lipomatous lesion with diffuse infiltration by benign appearing melanocytes within the fat lobules established by immunohistochemistry, which was positive for HMB45 and S100. This case serves to illustrate the initial diagnostic challenge in a male patient as well as the plasticity of the neural crest cells. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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