Sinus of Valsalva Aneurysm and Infective Endocarditis Involving a Bicuspid Aortic Valve in an Infant With Trisomy 21.
| Autor: | Croom NA, Therrien N, Chambliss M, Ursell PC |
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| Jazyk: | angličtina |
| Zdroj: | Academic forensic pathology [Acad Forensic Pathol] 2018 Sep; Vol. 8 (3), pp. 763-768. Date of Electronic Publication: 2018 Aug 31. |
| DOI: | 10.1177/1925362118797753 |
| Abstrakt: | A 19-month-old girl with trisomy 21 and a congenitally bicuspid aortic valve died following a short febrile illness. Autopsy disclosed pericarditis, epimyocardial abscess, infective endocarditis, and a sinus of Valsalva aneurysm. Microscopy demonstrated continuity between the aortic wall and valve leaflet, consistent with an acquired aneurysm. Abnormal hemodynamics associated with the valve malformation likely facilitated endocarditis. Competing Interests: Disclosures & Declaration of Conflicts of Interest: The authors, reviewers, editors, and publication staff do not report any relevant conflicts of interest |
| Databáze: | MEDLINE |
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