National Association of Medical Examiners Position Paper: Recommendations for the Investigation and Certification of Deaths in People with Epilepsy.

Autor: Middleton OL; Hennepin County Medical Examiner's Office., Atherton DS; University of Alabama at Birmingham, Anatomic Pathology, Division of Forensic Pathology., Bundock EA; Office of Chief Medical Examiner - Vermont State Department of Health., Donner E; Comprehensive Epilepsy Program, The Hospital for Sick Children - Toronto., Friedman D; NYU Comprehensive Epilepsy Center., Hesdorffer DC; Gertrude H. Sergievsky Center-Columbia University., Jarrell HS; University of New Mexico Health Sciences Center, Office of the Medical Investigator., McCrillis AM; New York University Langone Health, New York University School of Medicine., Mena OJ; Ventura County Office of Chief Medical Examiner., Morey M; Hennepin County Medical Examiner's Office., Thurman DJ; Emory University, School of Medicine, Department of Neurology., Tian N; Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Division of Population Health, Epilepsy Program., Tomson T; Department of Clinical Neuroscience, Karolinska Institutet, Department of Neurology, Karolinska University Hospital., Tseng ZH; University of California, San Francisco, Cardiac Electrophysiology Section, Cardiology Division., White S; Cook County Office of the Medical Examiner., Wright C; Stormlab Consulting., Devinsky O; NYU Comprehensive Epilepsy Center.
Jazyk: angličtina
Zdroj: Academic forensic pathology [Acad Forensic Pathol] 2018 Mar; Vol. 8 (1), pp. 119-135. Date of Electronic Publication: 2018 Mar 07.
DOI: 10.23907/2018.009
Abstrakt: Sudden unexpected death of an individual with epilepsy (SUDEP) can pose a challenge to death investigators, as most deaths are unwitnessed and the individual is commonly found dead in bed. Anatomic findings (e.g., tongue/lip bite) are commonly absent and of varying specificity, limiting the evidence to implicate epilepsy as a cause of or contributor to death. Thus, it is likely that death certificates significantly underrepresent the true number of deaths in which epilepsy was a factor. To address this, members of the National Association of Medical Examiners, North American SUDEP Registry, Epilepsy Foundation SUDEP Institute, American Epilepsy Society, and the Centers for Disease Control and Prevention convened an expert panel to generate evidence-based recommendations for the practice of death investigation and autopsy, toxicological analysis, interpretation of autopsy and toxicology findings, and death certification to improve the precision of death certificate data available for public health surveillance of epilepsy-related deaths. The recommendations provided in this paper are intended to assist medical examiners, coroners, and death investigators when a sudden, unexpected death in a person with epilepsy is encountered.
Competing Interests: DISCLOSURES & DECLARATION OF CONFLICTS OF INTEREST The opinions and conclusions of this paper have been reviewed and approved by the NAME Board of Directors and as such are endorsed by the National Association of Medical Examiners. These opinions and positions are based on a consensus of the current literature, knowledge, and prevailing theories on this topic. As scientific knowledge and experience grow and change, the National Association of Medical Examiners reserves the right to revise or update these opinions. The process by which NAME position papers are initiated, written, reviewed, and approved is publically available on the NAME website (www.thename.org). All scientific position papers endorsed by the National Association of Medical Examiners automatically expire five years after publication unless reaffirmed, revised, or retired at or before that time. This work is a product of NAME and as such, was not subjected to Academic Forensic Pathology editorial review. The findings and conclusions in this study are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. The authors, reviewers, editors, and publication staff do not report any relevant conflicts of interest This paper has been simultaneously published in Epilepsia, Volume 59, #3 and Academic Forensic Pathology: The Official Publication of the National Association of Medical Examiners, Volume 8, #1
Databáze: MEDLINE