IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation.

Autor: Metz R; New Link Genetics Corporation, Ames, IA, USA., Smith C; Lankenau Institute for Medical Research, Wynnewood, PA, USA., DuHadaway JB; Lankenau Institute for Medical Research, Wynnewood, PA, USA., Chandler P; Immunotherapy Center, Georgia Regents University, Augusta, GA, USA., Baban B; Immunotherapy Center, Georgia Regents University, Augusta, GA, USA., Merlo LMF; Lankenau Institute for Medical Research, Wynnewood, PA, USA., Pigott E; Lankenau Institute for Medical Research, Wynnewood, PA, USA., Keough MP; Lankenau Institute for Medical Research, Wynnewood, PA, USA., Rust S; New Link Genetics Corporation, Ames, IA, USA., Mellor AL; Immunotherapy Center, Georgia Regents University, Augusta, GA, USA., Mandik-Nayak L; Lankenau Institute for Medical Research, Wynnewood, PA, USA.; Department of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA, USA., Muller AJ; Lankenau Institute for Medical Research, Wynnewood, PA, USA.; Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA., Prendergast GC; Lankenau Institute for Medical Research, Wynnewood, PA, USA.; Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.; Department of Pathology, Anatomy and Cell Biology, Jefferson Medical School, Thomas Jefferson University, Philadelphia, PA, USA.
Jazyk: angličtina
Zdroj: International immunology [Int Immunol] 2019 Mar 05; Vol. 31 (3), pp. 181-182.
DOI: 10.1093/intimm/dxz003
Databáze: MEDLINE