Emergent multidrug-resistant nontyphoidal Salmonella serovars isolated from poultry in Brazil coharboring bla CTX-M-2 and qnrB or bla CMY-2 in large plasmids.

Autor: Penha Filho RAC; School of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, SP, Brazil, 14884-900. Electronic address: rafaelpenha12@yahoo.com.br., Ferreira JC; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil, 14040-903., Kanashiro AMI; Instituto Biológico de Descalvado, Descalvado, SP, Brazil, 13690-000., Berchieri Junior A; School of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal, SP, Brazil, 14884-900., Darini ALDC; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil, 14040-903.
Jazyk: angličtina
Zdroj: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2019 Sep; Vol. 95 (1), pp. 93-98. Date of Electronic Publication: 2019 Apr 29.
DOI: 10.1016/j.diagmicrobio.2019.04.003
Abstrakt: The number of foodborne gastroenteritis caused by nontyphoidal Salmonella (NTS) worldwide is estimated to be 80.3 million each year. Currently, antimicrobial-resistant NTS disseminated in the animal environment increases the risk of aggravated foodborne outbreaks. Poultry are important source of foodborne NTS infections. This study was conducted to evaluate the phenotypic and genotypic characteristics of 83 NTS isolates from poultry, classified within 36 different serovars. The most prevalent serovar was S. Schwarzengrund (10/83), from which 8/10 were multidrug resistant (MDR). The antimicrobial susceptibility testing showed a total of 18 MDR isolates, from which 8/18 coharbored bla CTX-M-2 and qnrB5. The genes qnrB5, bla CTX-M-2 , qnrB2, or bla CMY-2 were also found alone in other MDR isolates. All resistance genes were harbored in large plasmids, ranging from 30 to 270 kb. The pColE replicon was present in 8 MDR isolates; however it was not associated with resistance. ISCR1 and class I integron structures were always associated with bla CTX-M-2 .
(Copyright © 2019 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: