| Autor: |
Stopnitzky E; Department of Physics and Astronomy, University of Hawai'i at Mānoa, Honolulu, Hawai'i 96822, USA., Still S; Department of Physics and Astronomy, University of Hawai'i at Mānoa, Honolulu, Hawai'i 96822, USA.; Department of Information and Computer Sciences, University of Hawai'i at Mānoa, Honolulu, Hawai'i 96822, USA. |
| Jazyk: |
angličtina |
| Zdroj: |
Physical review. E [Phys Rev E] 2019 May; Vol. 99 (5-1), pp. 052101. |
| DOI: |
10.1103/PhysRevE.99.052101 |
| Abstrakt: |
The difficulty of obtaining appreciable quantities of biologically important molecules in thermodynamic equilibrium has long been identified as an obstacle to life's emergence, and determining the specific nonequilibrium conditions that might have given rise to life is challenging. To address these issues, we investigate how the concentrations of life's building blocks change as a function of the distance from equilibrium on average, in two example settings: (i) the synthesis of heavy amino acids and (ii) their polymerization into peptides. We find that relative concentrations of the heaviest amino acids can be boosted by four orders of magnitude, and concentrations of the longest peptide chains can be increased by hundreds of orders of magnitude. The average nonequilibrium distribution does not depend on the details of how the system was driven from equilibrium, indicating that environments might not have to be fine-tuned to support life. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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