Malignant pheochromocytoma with negative biochemical markers: Is it time to reclassify pheochromocytomas?

Autor:	Borzouei S; Clinical Research Development Unit of Shahid Beheshti Hospital, Hamadan University of Medical Science, Hamadan, Iran., Mousavi-Bahar SH; Urology & Nephrology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran., Salimbahrami SA; Clinical Research Development Unit of Farshchian Heart Center, Department of Anesthesiology, School of Medicine, Hamadan University of Medical Science, Hamadan, Iran., Sardari Masihi M; Resident of Urology, School of Medicine, Urology Department, Hamadan University of Medical Sciences, Hamadan, Iran.
Jazyk:	angličtina
Zdroj:	Urology case reports [Urol Case Rep] 2019 Mar 05; Vol. 24, pp. 100858. Date of Electronic Publication: 2019 Mar 05 (Print Publication: 2019).
DOI:	10.1016/j.eucr.2019.100858
Abstrakt:	Pheochromocytomas are catecholamine producing tumors of adrenal gland generally diagnosed by presence of these markers in urine or plasma. However, a few may be marker-negative and challenging for clinicians. Several reports of these marker-negative pheochromocytomas may warrant necessity for a new classification of these tumors. Adrenergic blockade before surgery is one of the main reasons for recognition of these cases. We present a case of marker-negative pheochromocytoma which turned out to be malignant on its recurrence. To our knowledge, this is the only case of malignant marker-negative pheochromocytoma reported in literature so far.
Databáze:	MEDLINE
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