Granular cell cutaneous epithelioid angiomatous nodule.

Autor: Sorrells TC; Department of Pathology, Naval Medical Center, San Diego, California., Winn A; Department of Dermatology, Naval Medical Center, San Diego, California., Sulit DJ; Department of Dermatology, Naval Medical Center, San Diego, California.
Jazyk: angličtina
Zdroj: Journal of cutaneous pathology [J Cutan Pathol] 2019 Nov; Vol. 46 (11), pp. 864-866. Date of Electronic Publication: 2019 Jul 08.
DOI: 10.1111/cup.13527
Abstrakt: Cutaneous epithelioid angiomatous nodule is an uncommon vascular lesion usually described as composed of epithelioid endothelial cells with vesicular nuclei and eosinophilic cytoplasm. A granular cell variant has not been previously described. Endothelial cells can present with granular cytoplasm as documented with reports of granular cell angiosarcoma. The granularity is thought to be due to increased intracytoplasmic lysosomes. We present a case of a benign superficial vascular lesion composed of a sheet-like proliferation of epithelioid endothelial cells with distinctly granular cytoplasm confirmed as of endothelial origin with positive staining for CD31 and ERG.
(Published 2019. This article is a U.S. Government work and is in the public domain in the USA.)
Databáze: MEDLINE
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