Mimickers of neuropsychiatric manifestations in systemic lupus erythematosus.

Autor: de Amorim JC; Graduate Program of Child and Adolescent Health, School of Medical Science, University of Campinas, Brazil; Laboratory of Autoimmune Diseases, School of Medical Science, University of Campinas, Brazil., Torricelli AK; Rheumatology Unit, University of São Paulo, Brazil., Frittoli RB; Laboratory of Autoimmune Diseases, School of Medical Science, University of Campinas, Brazil; Graduate Program of Physiopathology, School of Medical Science, University of Campinas, Brazil., Lapa AT; Graduate Program of Child and Adolescent Health, School of Medical Science, University of Campinas, Brazil; Laboratory of Autoimmune Diseases, School of Medical Science, University of Campinas, Brazil., Dertkigil SSJ; Department of Radiology, School of Medical Science, University of Campinas, Brazil., Reis F; Department of Radiology, School of Medical Science, University of Campinas, Brazil., Costallat LT; Rheumatology Unit, Department of Medicine, School of Medical Science, University of Campinas, Brazil., França Junior MC; Department of Neurology, School of Medical Science, University of Campinas, Brazil., Appenzeller S; Laboratory of Autoimmune Diseases, School of Medical Science, University of Campinas, Brazil; Rheumatology Unit, Department of Medicine, School of Medical Science, University of Campinas, Brazil. Electronic address: appenzel@unicamp.br.
Jazyk: angličtina
Zdroj: Best practice & research. Clinical rheumatology [Best Pract Res Clin Rheumatol] 2018 Oct; Vol. 32 (5), pp. 623-639. Date of Electronic Publication: 2019 Feb 22.
DOI: 10.1016/j.berh.2019.01.020
Abstrakt: Systemic lupus erythematosus (SLE), presenting with new onset or worsening neuropsychiatric (NP) symptoms, is a challenge in clinical practice. Mimickers such as infections, drug-induced side effects, metabolic abnormalities, malignancies, and alcohol-related disorders have to be excluded, before attributing the manifestations to disease activity. Proper diagnosis is essential to guide adequate management and reduce morbidity and mortality. In this review article, we will highlight clinical, laboratorial, and neuroradiological features that are helpful to assist in the differential diagnosis.
(Copyright © 2019. Published by Elsevier Ltd.)
Databáze: MEDLINE
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