Nash-wo-Numa (childhood growth & development) study protocol: factors that impact linear growth in children 9 to 15 years of age in Matiari, Pakistan.

Autor: Campisi SC; Centre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.; Faculty of Medicine, Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada., Wasan Y; Division of Women and Child Health, Aga Khan University, Karachi, Pakistan., Soofi S; Division of Women and Child Health, Aga Khan University, Karachi, Pakistan., Monga S; Psychiatry, The Hospital for Sick Children, Toronto, Ontario, Canada.; Psychiatry, University of Toronto, Toronto, Ontario, Canada., Korczak DJ; Psychiatry, The Hospital for Sick Children, Toronto, Ontario, Canada.; Psychiatry, University of Toronto, Toronto, Ontario, Canada., Lou W; Dalla Lana School of Public Health, University of Toronto Dalla Lana School of Public Health, Toronto, Ontario, Canada., Soder O; Department of Women's and Children's Health, Karolinska Universitetssjukhuset, Stockholm, Sweden., Vandermorris A; Centre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Adolescent Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada., Humayun KN; Paediatrics, Aga Khan University Hospital, Karachi, Pakistan., Mian A; Psychiatry, Aga Khan University, Karachi, Pakistan., Szatmari P; Psychiatry, The Hospital for Sick Children, Toronto, Ontario, Canada.; Psychiatry, University of Toronto, Toronto, Ontario, Canada.; Centre for Child and Youth Depression, Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Bhutta ZA; Centre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.; Faculty of Medicine, Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.; Division of Women and Child Health, Aga Khan University, Karachi, Pakistan.; Dalla Lana School of Public Health, University of Toronto Dalla Lana School of Public Health, Toronto, Ontario, Canada.
Jazyk: angličtina
Zdroj: BMJ open [BMJ Open] 2019 Jun 12; Vol. 9 (6), pp. e028343. Date of Electronic Publication: 2019 Jun 12.
DOI: 10.1136/bmjopen-2018-028343
Abstrakt: Introduction: Adolescence is a time of significant physical and emotional change, and there is emerging concern that adolescents living in low- and middle-income countries (LMIC) may face substantial challenges in relation to linear growth and mental health. Data on the global burden of stunting after 5 years of age are limited, but estimates suggest up to 50 per cent of all adolescents in some LMIC are stunted. Additionally, many LMIC lack robust mental health care delivery systems. Pakistan has one of the world's largest populations of adolescents (10 to 19 years) at approximately 40 million. The Nash-wo-Numa study's primary objective is to assess the prevalence and risk factors for stunting among early adolescents in rural Pakistan. The study also aims to determine the prevalence of poor mental health and identify factors associated with common mental health concerns during the childhood to adulthood transition.
Methods: This cross-sectional study will include girls (n= 738) 9.0 to 14.9 years of age and boys (n=687) 10.0 to 15.9 years of age who live in the rural district of Matiari, Pakistan. Participants will be assessed for anthropometrical measures, puberty development, nutritional biomarkers as well as symptoms of depression, anxiety and trauma using validated scales.
Ethics and Dissemination: The proposed study aims to complete the picture of child and adolescent health concerning linear growth and mental health by including puberty indicators. Ethics approval has been granted by the Ethics Review Committee at the Aga Khan University, Karachi, Pakistan, #5251-WCH-ERC-18 and Research Ethics Board at SickKids Hospital, Toronto, Canada, #:1000060684. Study results will be presented at relevant conferences and published in peer-reviewed journals.
Trial Registration Number: NCT03647553; Pre-results.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE