| Autor: |
Baby PM; Department of Physiology, Melaka Manipal Medical College (Manipal Campus), Manipal Academy of Higher Education, Karnataka, India., Kumar P; Department of Plastic Surgery, Kasturba Medical College - Manipal, Manipal Academy of Higher Education, Karnataka, India., Kumar R; Department of Radiotherapy Oncology, Kasturba Medical College - Manipal, Manipal Academy of Higher Education, Karnataka, India., Jacob SS; Department of Physiology, Kasturba Medical College - Manipal, Manipal Academy of Higher Education, Karnataka, India., Rawat D; Department of Radiotherapy Oncology, Kasturba Medical College - Manipal, Manipal Academy of Higher Education, Karnataka, India., Vs B; Department of Statistics, Manipal Academy of Higher Education, Manipal, Karnataka, India., Karun KM; Department of Statistics, Manipal Academy of Higher Education, Manipal, Karnataka, India., Bhat NB; Department of Microbiology, Melaka Manipal Medical College (Manipal Campus), Manipal Academy of Higher Education, Karnataka, India. |
| Abstrakt: |
Though often used in cardiac intensive monitoring set up, simultaneous evaluation of several variables like CVP, PCWP, SVV and hTEE for fluid volume resuscitation (especially when capillary permeability is major problem than cardiac performance) is a major challenge in many ICU setups. Therefore, repetitive determination of blood volume by trivalent chromium [ 51 Cr (III)] as a direct single variable method may be a near ideal method during fluid volume resuscitation in cases where capillary permeability is a major problem (e.g. Burns). Hence, in the present article the repeatability and reliability of 51 Cr (III) method in New Zealand white rabbits was explored. Mean blood volume values of initial measurement were 195.66 ± 47.30 ml or 89.81 ± 17.88 ml/kg body weight. Repeated mean blood volume values, measured after 1 h, was 181.98 ± 53.16 ml or 83.68 ± 22.09 ml/kg body weight. The average difference between the initial and repeated measurements was 10.93 ml (95% CI -3.33, 25.19 ml), which is not statistically significant (P = 0.128). The method using 51 Cr (III) for repeat blood volume measurements after sixty minutes in rabbits is a reliable method. •Rapid•Repeatable•Reliable. |
