[Whipple's disease: very rare, fatal without treatment but easily cured].

Autor: Melas N; Uppsala Universitet - Centrum för forskning och utveckling Region Gävleborg Gävle, Sweden Gavle sjukhus - Gastroenterologmottagning Gavle, Sweden., Haji Younes A; Uppsala Universitet - Centrum för forskning och utveckling Gävle, Sweden Uppsala Universitet Medicinska och farmaceutiska vetenskapsomradet - Centrum för forskning och utveckling Gävleborg Uppsala, Sweden., Egerszegi P; Gavle sjukhus - Klinisk patologi och cytologi Gavle, Sweden Gavle sjukhus - Gastroenterologmottagning Gavle, Sweden.
Jazyk: švédština
Zdroj: Lakartidningen [Lakartidningen] 2019 May 28; Vol. 116. Date of Electronic Publication: 2019 May 28.
Abstrakt: Whipple's disease is a chronic infectious disease that primarily affects the small intestine, but several organs can be involved simultaneously. The disease is caused by a gram-positive bacterium called Tropheryma whipplei. The disease is difficult to suspect because it is rare, and produces unspecific and long-term symptoms. Whipple's disease can lead to death if not treated. We here present a case of a man who presented with gastrointestinal symptoms in the form of diarrhea with blood, weight loss, fever, and lymphadenopathy and who was finally diagnosed with Whipple's disease 4 years after the occurrence of manifestations from the joints. The diagnosis was made both with 16S rRNA against Tropheryma whipplei and histopathologically from biopsy taken from the duodenum and distal ileum. The purpose of this case report is to raise awareness of a very rare disease that presented with a combination of symptoms similar to other and significantly more common diseases.
Databáze: MEDLINE