Relaxation Properties of Contrast Media for MRI Based on Iron Oxide Nanoparticles in Different Magnetic Fields.

Autor: Chekhonin VP; N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia., Abakumov MA; N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia., Mazhuga AG; D. I. Mendeleev University of Chemical Technology of Russia, Moscow, Russia., Bagdinova AN; P. N. Lebedev Physical Institute of the Russian Academy of Sciences, Moscow, Russia. anna.bagdinova@gmail.com., Demikhov EI; P. N. Lebedev Physical Institute of the Russian Academy of Sciences, Moscow, Russia., Demikhov TE; P. N. Lebedev Physical Institute of the Russian Academy of Sciences, Moscow, Russia., Mishkinis BY; S. P. HELPIC, Moscow, Russia., Konstantinov MV; P. N. Lebedev Physical Institute of the Russian Academy of Sciences, Moscow, Russia., Tarasov VP; P. N. Lebedev Physical Institute of the Russian Academy of Sciences, Moscow, Russia., Shumm BA; P. N. Lebedev Physical Institute of the Russian Academy of Sciences, Moscow, Russia., Gippius AA; P. N. Lebedev Physical Institute of the Russian Academy of Sciences, Moscow, Russia., Gervits NV; P. N. Lebedev Physical Institute of the Russian Academy of Sciences, Moscow, Russia., Shumm AB; P. N. Lebedev Physical Institute of the Russian Academy of Sciences, Moscow, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2019 May; Vol. 167 (1), pp. 97-99. Date of Electronic Publication: 2019 Jun 10.
DOI: 10.1007/s10517-019-04469-1
Abstrakt: We studied dependences of T2 relaxation time on magnetic field and concentration of nanoparticles. It was found that nanocontrast media are effective under the influence of the magnetic fields in the range 0.3-7 T. Data of electron paramagnetic resonance confirm the assumption on aggregation of nanoparticles not coated with proteins in high magnetic fields.
Databáze: MEDLINE