The relationship between vitamin D level and hepatosteatosis in obese children.

Autor:	Dursun F; Department of Pediatric Endocrinology, Umraniye Training and Research Hospital, Istanbul, Turkey., Gerenli N; Department of Pediatric Gastroenterology, Umraniye Training and Research Hospital, Istanbul, Turkey., Dur SMS; Department of Radiology, Umraniye Training and Research Hospital, Istanbul, Turkey., Kirmizibekmez H; Department of Pediatric Endocrinology, Umraniye Training and Research Hospital, Istanbul, Turkey.
Jazyk:	angličtina
Zdroj:	Northern clinics of Istanbul [North Clin Istanb] 2018 Aug 08; Vol. 6 (1), pp. 28-32. Date of Electronic Publication: 2018 Aug 08 (Print Publication: 2019).
DOI:	10.14744/nci.2018.26097
Abstrakt:	Objective: The increasing incidence of obesity in children is a significant risk factor for nonalcoholic fatty liver disease and obesity-associated morbidity. In the present study, we aimed to explore the correlation between Vitamin D level and hepatosteatosis in obese children. Methods: A total of 110 children aged 10-16 years who presented to pediatric endocrinology outpatient clinic for obesity were enrolled. The study was completed in a single season between September and November. Hepatosteatosis was diagnosed by ultrasonography. The patients were grouped into two groups: Group 1 comprised patients with hepatosteatosis and Group 2 consisted of patients without hepatosteatosis. 25 hydroxy (25-OH) Vitamin D levels were compared between patients with and without hepatosteatosis. Results: No statistically significant difference was observed between 25-OH Vitamin D levels of patients with and without hepatosteatosis. When the effects of age and sex were kept constant, there was no significant correlation between Vitamin D level and aspartate aminotransferase, alanine aminotransferase, and body mass index values. Conclusion: Unlike the results of the previous studies, we were unable to detect any significant difference between Vitamin D levels of obese patients with and without hepatosteatosis. We think that obesity, rather than Vitamin D status, that is, in fact, independently associated with nonalcoholic fatty liver disease. Larger studies are needed to investigate the impact of Vitamin D in children with obesity with hepatosteatosis. Competing Interests: Conflict of Interest: The authors declare no conflict of interest.
Databáze:	MEDLINE
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